Literature DB >> 31268097

Tuning the solubility of ionophores: glutathione-mediated transport of chloride ions across hydrophobic membranes.

Nasim Akhtar1, Nirmalya Pradhan1, Abhishek Saha1, Vishnu Kumar2, Oindrila Biswas1, Subhasis Dey1, Manisha Shah2, Sachin Kumar2, Debasis Manna1.   

Abstract

A stimuli-responsive anion transport strategy was successfully employed to regulate the water solubility of ionophores and promote controlled transport of Cl- ions across lipid bilayers. A sulfonium-based proanionophore was efficiently activated by glutathione to regenerate the active anionophore, which allowed controlled transport of Cl- ions in a cellular environment with lower cytotoxicity.

Entities:  

Year:  2019        PMID: 31268097     DOI: 10.1039/c9cc04518j

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  3 in total

1.  Photomodulation of Transmembrane Transport and Potential by Stiff-Stilbene Based Bis(thio)ureas.

Authors:  Sander J Wezenberg; Li-Jun Chen; Jasper E Bos; Ben L Feringa; Ethan N W Howe; Xin Wu; Maxime A Siegler; Philip A Gale
Journal:  J Am Chem Soc       Date:  2021-12-21       Impact factor: 15.419

2.  Redox-controlled chalcogen and pnictogen bonding: the case of a sulfonium/stibonium dication as a preanionophore for chloride anion transport.

Authors:  Gyeongjin Park; François P Gabbaï
Journal:  Chem Sci       Date:  2020-09-10       Impact factor: 9.825

Review 3.  Recent Advances in Bioactive Artificial Ionophores.

Authors:  Arundhati Roy; Pinaki Talukdar
Journal:  Chembiochem       Date:  2021-06-23       Impact factor: 3.164

  3 in total

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