Fatih Mehmet Türkcü1, Alparslan Şahin2, Ümit Karaalp3, Yasin Çınar4, Muhammed Şahin5, Zeynep Gürsel Özkurt4, Uğur Keklikçi4. 1. Department of Ophthalmology, Bower Private Hospital, Diyarbakir, Turkey. 2. Department of Ophthalmology, Batman Zilan Hospital, Batman, Turkey. 3. Department of Ophthalmology, Batman State Hospital, Batman, Turkey. 4. School of Medicine, Department of Ophthalmology, Dicle University, Diyarbakir, Turkey. 5. School of Medicine, Department of Ophthalmology, Dicle University, Diyarbakir, Turkey. drmuhammedsahin@gmail.com.
Abstract
PURPOSE: To measure the vascular density (VD) and foveal avascular zone (FAZ) area in patients with Behçet's disease (BD) obtained by optical coherence tomography angiography (OCTA). METHODS: VD and FAZ area in the deep and superficial retinal vascular networks were measured in all eyes. RESULTS: Thirty BD and 31 control subjects were included in the study. The mean overall VD measured in the entire scan was lower in BD compared with control group in both the superficial (49.52 ± 6.54 vs 53.57 ± 2.87%, respectively; p = 0.003) and deep (53.44 ± 7.44 vs 58.41 ± 3.01%, respectively; p = 0.002) areas. The FAZ in the BD group was significantly increased at the level of the superficial (0.52 ± 0.67 vs 0.28 ± 0.1 mm2, respectively; p = 0.05) and deep (0.91 ± 1.25 vs 0.39 ± 0.14 mm2, respectively; p = 0.024) areas compared with those of the control group. The deep and the superficial FAZ areas were positively correlated with disease duration and negatively with VA. CONCLUSION: In the patients with BD, OCTA showed decreased VD in both the superficial and deep retinal vascular networks. Besides, the VA was correlated with the VD and FAZ.
PURPOSE: To measure the vascular density (VD) and foveal avascular zone (FAZ) area in patients with Behçet's disease (BD) obtained by optical coherence tomography angiography (OCTA). METHODS: VD and FAZ area in the deep and superficial retinal vascular networks were measured in all eyes. RESULTS: Thirty BD and 31 control subjects were included in the study. The mean overall VD measured in the entire scan was lower in BD compared with control group in both the superficial (49.52 ± 6.54 vs 53.57 ± 2.87%, respectively; p = 0.003) and deep (53.44 ± 7.44 vs 58.41 ± 3.01%, respectively; p = 0.002) areas. The FAZ in the BD group was significantly increased at the level of the superficial (0.52 ± 0.67 vs 0.28 ± 0.1 mm2, respectively; p = 0.05) and deep (0.91 ± 1.25 vs 0.39 ± 0.14 mm2, respectively; p = 0.024) areas compared with those of the control group. The deep and the superficial FAZ areas were positively correlated with disease duration and negatively with VA. CONCLUSION: In the patients with BD, OCTA showed decreased VD in both the superficial and deep retinal vascular networks. Besides, the VA was correlated with the VD and FAZ.
Authors: Florence Coscas; Agnes Glacet-Bernard; Alexandra Miere; Violaine Caillaux; Joel Uzzan; Marco Lupidi; Gabriel Coscas; Eric H Souied Journal: Am J Ophthalmol Date: 2015-10-23 Impact factor: 5.258
Authors: Wasim A Samara; Abtin Shahlaee; Jayanth Sridhar; M Ali Khan; Allen C Ho; Jason Hsu Journal: Am J Ophthalmol Date: 2016-03-31 Impact factor: 5.258