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Literature DB >> 31267067

Trends in clinical success rates and therapeutic focus.

Helen Dowden, Jamie Munro.

Abstract

Keywords: Drug discovery

Year: 2019 PMID： 31267067 DOI： 10.1038/d41573-019-00074-z

Source DB: PubMed Journal: Nat Rev Drug Discov ISSN： 1474-1776 Impact factor: 84.694

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Cited

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47 in total

1. Translational misconceptions.

Authors: Christopher P Austin
Journal: Nat Rev Drug Discov Date: 2021-07 Impact factor: 84.694

Review 2. The promise and reality of therapeutic discovery from large cohorts.

Authors: Eugene Melamud; D Leland Taylor; Anurag Sethi; Madeleine Cule; Anastasia Baryshnikova; Danish Saleheen; Nick van Bruggen; Garret A FitzGerald
Journal: J Clin Invest Date: 2020-02-03 Impact factor: 14.808

Review 3. Toxicity testing is evolving!

Authors: Ida Fischer; Catherine Milton; Heather Wallace
Journal: Toxicol Res (Camb) Date: 2020-04-24 Impact factor: 3.524

4. Further exploration of the structure-activity relationship of dual soluble epoxide hydrolase/fatty acid amide hydrolase inhibitors.

Authors: Stephanie Wilt; Sean Kodani; Leah Valencia; Paula K Hudson; Stephanie Sanchez; Taylor Quintana; Christophe Morisseau; Bruce D Hammock; Ram Kandasamy; Stevan Pecic
Journal: Bioorg Med Chem Date: 2021-11-11 Impact factor: 3.641

5. Side effect prediction based on drug-induced gene expression profiles and random forest with iterative feature selection.

Authors: Arzu Cakir; Melisa Tuncer; Hilal Taymaz-Nikerel; Ozlem Ulucan
Journal: Pharmacogenomics J Date: 2021-06-21 Impact factor: 3.550

Review 6. Integrating genomics with biomarkers and therapeutic targets to invigorate cardiovascular drug development.

Authors: Michael V Holmes; Tom G Richardson; Brian A Ference; Neil M Davies; George Davey Smith
Journal: Nat Rev Cardiol Date: 2021-03-11 Impact factor: 32.419

7. Physicochemical Profiling and Comparison of Research Antiplasmodials and Advanced Stage Antimalarials with Oral Drugs.

Authors: Amritansh Bhanot; Sandeep Sundriyal
Journal: ACS Omega Date: 2021-02-25