Literature DB >> 31266528

Correction to: Celastrol mediates autophagy and apoptosis via the ROS/JNK and Akt/mTOR signaling pathways in glioma cells.

Xihong Liu1,2, Peiyuan Zhao3, Xiujuan Wang4,5, Lei Wang1,2, Yingjun Zhu1,2, Yadi Song1,2, Wei Gao6,7,8.   

Abstract

In the original publication of this article [1], there are two errors.

Entities:  

Year:  2019        PMID: 31266528      PMCID: PMC6604141          DOI: 10.1186/s13046-019-1285-x

Source DB:  PubMed          Journal:  J Exp Clin Cancer Res        ISSN: 0392-9078


Correction to: J Exp Clin Cancer Res (2019) 38:184 https://doi.org/10.1186/s13046-019-1173-4 In the original publication of this article [1], there are two errors. The first error is in author affiliation information. The corrected author affiliation information is as given hereafter: Xihong Liu1, Peiyuan Zhao4, Xiujuan Wang1*, Lei Wang1, Yingjun Zhu1, Yadi Song1 and Wei Gao1,2,3*. 1 School of Traditional Chinese Medicine, Beijing Key Lab of TCM Collateral Disease Theory Research, Capital Medical University, Beijing, China. 2 School of Pharmaceutical Sciences, Capital Medical University, Beijing, China. 3 Advanced Innovation Center for Human Brain Protection, Capital Medical University, Beijing, China. 4 Basic Discipline of Integrated Chinese and Western Medicine, Henan University of Chinese Medicine, Henan, China. The second error is in Fig. 8d (panel 2 of Tunel assay, group of 1 mg/kg Cel). The revised Fig. 8 which includes 8d has now been included in this correction.
Fig. 8

Celastrol suppressed the growth of orthotopic xenografts of U251 cells in vivo. a One week after inoculation, MRI scanning of glioma was performed on a 7.0 T MR scanner. b One week after inoculation, H&E staining of tumor tissue was carried out. Scale bars = 50 μm (c) Tumor volumes determined by MRI at 0, 7 and 14 days after inoculation in the 5 different groups. d Tunel assay and immunohistochemical staining of tumor specimens. Scale bars = 50 μm. e The levels of cleaved caspase-3, LC3B, p-JNK, p-Akt and p-mTOR in tumor tissues were detected by western blotting. β-actin was used as an internal control. Data are presented as the Mean ± SD (n = 3). *P < 0.05, **P < 0.01, ***P < 0.001, significantly different compared with the untreated control group

Celastrol suppressed the growth of orthotopic xenografts of U251 cells in vivo. a One week after inoculation, MRI scanning of glioma was performed on a 7.0 T MR scanner. b One week after inoculation, H&E staining of tumor tissue was carried out. Scale bars = 50 μm (c) Tumor volumes determined by MRI at 0, 7 and 14 days after inoculation in the 5 different groups. d Tunel assay and immunohistochemical staining of tumor specimens. Scale bars = 50 μm. e The levels of cleaved caspase-3, LC3B, p-JNK, p-Akt and p-mTOR in tumor tissues were detected by western blotting. β-actin was used as an internal control. Data are presented as the Mean ± SD (n = 3). *P < 0.05, **P < 0.01, ***P < 0.001, significantly different compared with the untreated control group The correct Fig. 8 is given hereafter: The error: In the initially published version of this article, the picture in the Tunel assay of Cel (1 kg/mg) group are the same with that in Cel (2 kg/mg) group in Fig. 8d. This error does not affect discussions and conclusions drawn in the article.
  1 in total

1.  Celastrol mediates autophagy and apoptosis via the ROS/JNK and Akt/mTOR signaling pathways in glioma cells.

Authors:  Xihong Liu; Peiyuan Zhao; Xiujuan Wang; Lei Wang; Yingjun Zhu; Yadi Song; Wei Gao
Journal:  J Exp Clin Cancer Res       Date:  2019-05-03
  1 in total
  3 in total

1.  ERK inhibition in glioblastoma is associated with autophagy activation and tumorigenesis suppression.

Authors:  Kang Yang; Lan Luan; Xinyu Li; Xu Sun; Jian Yin
Journal:  J Neurooncol       Date:  2021-11-19       Impact factor: 4.130

2.  Sempervirine Mediates Autophagy and Apoptosis via the Akt/mTOR Signaling Pathways in Glioma Cells.

Authors:  Gaopan Li; Yuhuan Zhong; Wenyi Wang; Xiaokang Jia; Huaichang Zhu; Wenwen Jiang; Yu Song; Wen Xu; Shuisheng Wu
Journal:  Front Pharmacol       Date:  2021-11-30       Impact factor: 5.810

3.  The Synergistic Effects of Celastrol in combination with Tamoxifen on Apoptosis and Autophagy in MCF-7 Cells.

Authors:  Lijun Wang; Luqun Tang; Chengyun Yao; Chunyan Liu; Yongqian Shu
Journal:  J Immunol Res       Date:  2021-07-22       Impact factor: 4.818

  3 in total

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