Liz Ruiz-Estigarribia1, Miguel Ángel Martínez-González2, Jesús Díaz-Gutiérrez1, Almudena Sánchez-Villegas3, Francisca Lahortiga-Ramos4, Maira Bes-Rastrollo5. 1. University of Navarra, Department of Preventive Medicine and Public Health, School of Medicine, Pamplona, Spain. 2. University of Navarra, Department of Preventive Medicine and Public Health, School of Medicine, Pamplona, Spain; CIBER Pathophysiology of Obesity and Nutrition (CIBERobn), Institute of Health Carlos III, Madrid, Spain; IDISNA Navarra's Health Research Institute, Pamplona, Spain; Department of Nutrition, Harvard TH Chan School of Public Health, Boston, MA, United States. Electronic address: mamartinez@unav.es. 3. CIBER Pathophysiology of Obesity and Nutrition (CIBERobn), Institute of Health Carlos III, Madrid, Spain; Nutrition Research group, Research Institute of Biomedical and Health Sciences, University of Las Palmas de Gran Canaria, Spain. 4. Department of Psychiatry and Medical Psychology, University Clinic of Navarra, Spain. 5. University of Navarra, Department of Preventive Medicine and Public Health, School of Medicine, Pamplona, Spain; CIBER Pathophysiology of Obesity and Nutrition (CIBERobn), Institute of Health Carlos III, Madrid, Spain; IDISNA Navarra's Health Research Institute, Pamplona, Spain.
Abstract
BACKGROUND: Lifestyles are involved in the pathogenesis of depression and many of these factors can be modified for the potential prevention of depression. Our aim was to assess the association between a healthy-lifestyle score, that includes some less-studied lifestyle indicators, and the risk of depression. METHODS: We followed 14,908 participants initially free of any history of depression in the "Seguimiento Universidad de Navarra" (SUN) cohort. Information was collected biennially from 1999 to December 2016. We calculated a healthy-lifestyle score (0-10 points), previously associated with cardioprotection, by giving one point to each of the following components: never smoking, physical activity (> 20 METs-h/week), Mediterranean diet adherence (≥ 4 points), healthy body mass index (≤ 22 kg/m2), moderate alcohol consumption (women 0.1-5 g/d; men 0.1-10 g/d of ethanol), avoidance of binge drinking (never more than 5 alcoholic drinks in a row), low television exposure (≤ 2 h/d), short afternoon nap (≤ 30 min/day), time spent with friends (>1 h/d) and working at least 40 h/week. RESULTS: During a median follow-up of 10.4 years, we observed 774 new cases of major depression among participants initially free of depression. The highest category (8-10 factors) showed a significant inverse association with a 32% relative risk reduction for depression compared to the lowest category (0-3 factors) (multivariable-adjusted hazard ratio: 0.68; 95% CI:0.49-0.95) (p for trend = 0.010). CONCLUSIONS: Adopting a healthy-lifestyle was associated with a lower risk of incident depression in the SUN cohort. This index, including ten simple healthy lifestyle habits, may be useful for a more integrative approach to depression prevention.
BACKGROUND: Lifestyles are involved in the pathogenesis of depression and many of these factors can be modified for the potential prevention of depression. Our aim was to assess the association between a healthy-lifestyle score, that includes some less-studied lifestyle indicators, and the risk of depression. METHODS: We followed 14,908 participants initially free of any history of depression in the "Seguimiento Universidad de Navarra" (SUN) cohort. Information was collected biennially from 1999 to December 2016. We calculated a healthy-lifestyle score (0-10 points), previously associated with cardioprotection, by giving one point to each of the following components: never smoking, physical activity (> 20 METs-h/week), Mediterranean diet adherence (≥ 4 points), healthy body mass index (≤ 22 kg/m2), moderate alcohol consumption (women 0.1-5 g/d; men 0.1-10 g/d of ethanol), avoidance of binge drinking (never more than 5 alcoholic drinks in a row), low television exposure (≤ 2 h/d), short afternoon nap (≤ 30 min/day), time spent with friends (>1 h/d) and working at least 40 h/week. RESULTS: During a median follow-up of 10.4 years, we observed 774 new cases of major depression among participants initially free of depression. The highest category (8-10 factors) showed a significant inverse association with a 32% relative risk reduction for depression compared to the lowest category (0-3 factors) (multivariable-adjusted hazard ratio: 0.68; 95% CI:0.49-0.95) (p for trend = 0.010). CONCLUSIONS: Adopting a healthy-lifestyle was associated with a lower risk of incident depression in the SUN cohort. This index, including ten simple healthy lifestyle habits, may be useful for a more integrative approach to depression prevention.
Authors: Fan-Yun Lan; Christopher Scheibler; Maria Soledad Hershey; Juan Luis Romero-Cabrera; Gabriel C Gaviola; Ioanna Yiannakou; Alejandro Fernandez-Montero; Costas A Christophi; David C Christiani; Mercedes Sotos-Prieto; Stefanos N Kales Journal: Sci Rep Date: 2022-06-23 Impact factor: 4.996
Authors: Aina Riera-Sampol; Miquel Bennasar-Veny; Pedro Tauler; Mar Nafría; Miquel Colom; Antoni Aguilo Journal: Nutrients Date: 2021-02-10 Impact factor: 5.717