Literature DB >> 3126411

Protein redistribution diet restores motor function in patients with dopa-resistant "off" periods.

J H Pincus1, K Barry.   

Abstract

Sixteen parkinsonians with acquired drug-resistant "off" periods without dyskinesia were placed on a diet in which virtually all protein was concentrated in the evening meal. Restoration of sensitivity to levodopa resulted in 88%. Ten patients (62%) have continued to comply with the diet for 7 months (mean). Two patients were studied in detail. Immobility correlated with elevated plasma levels of large neutral amino acids (LNAA), normality with low LNAA.

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Year:  1988        PMID: 3126411     DOI: 10.1212/wnl.38.3.481

Source DB:  PubMed          Journal:  Neurology        ISSN: 0028-3878            Impact factor:   9.910


  12 in total

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5.  Influence of fluctuations of plasma large neutral amino acids with normal diets on the clinical response to levodopa.

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