| Literature DB >> 31262176 |
Kseniya V Belyaeva1, Lina P Nikitina1, Anastasiya G Mal'kina1, Andrei V Afonin1, Alexander V Vashchenko1, Boris A Trofimov1.
Abstract
Arylcyanoacetylenes trigger the assembly of dihydropyrimido[1,2-a]quinolin-3-ones in good to excellent yields on the platform of quinolines in the presence of KOH in aqueous media at room temperature. This green on-water methodology provides a simple one-pot access to a novel family of the pharmaceutically prospective compounds.Entities:
Year: 2019 PMID： 31262176 DOI： 10.1021/acs.joc.9b01482
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354