| Literature DB >> 31261248 |
Wei Wang1, L Jeffrey Medeiros.
Abstract
Cyclin D1, encoded by CCND1, promotes cell cycle progression from G1 to S phase. Its expression is induced by MAPK/ERK pathway as well as translocations/rearrangements involving CCND1 gene. The evaluation of cyclin D1 expression by immunohistochemistry plays an important role in the diagnostic workup of various hematopoietic diseases. In this review, we aimed to discuss the value of cyclin D1 immunostain in the diagnosis and different diagnosis of hematopoietic neoplasms.Entities:
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Year: 2019 PMID： 31261248 DOI： 10.1097/PAP.0000000000000241
Source DB: PubMed Journal: Adv Anat Pathol ISSN： 1072-4109 Impact factor: 3.875