Jeffrey Powell1, Scott Isom2, Jasmin Divers2, Anna Bellatorre3, Melissa Johnson3, Janelia Smiley1, Quanna Begay1, Christine Benally1, Diana Hu4, Sharon Saydah5, David J Pettitt6, Catherine Pihoker7, Dana Dabelea3. 1. Community Health Division, Shiprock Service Unit, Navajo Area Indian Health Service, Shiprock, NM. 2. Department of Biostatistics, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina. 3. Department of Epidemiology, Colorado School of Public Health, University of Colorado Denver, Aurora, Colorado. 4. Pediatrics Department, Tuba City Regional Health Care Center, Tuba City, Arizona. 5. Division of Diabetes Translation, Centers for Disease Control and Prevention, Atlanta, Georgia. 6. Santa Barbara, California. 7. Department of Pediatrics, University of Washington, Seattle, WA.
Abstract
AIM: SEARCH has recently reported that both prevalence and incidence of youth onset type 2 diabetes (YT2D) increased among most US race/ethnic groups in the early 2000s. This study reports on the incidence (2002-2013) and prevalence (2001, 2009) of YT2D in the Navajo Nation among youth age < 20 years from 2001 to 2013. METHODS: SEARCH sought to identify prevalent YT2D cases in 2001 (N = 75) and 2009 (N = 70) and all incident YT2D cases in three periods: 2002 to 2005 (N = 53), 2006 to 2009 (N = 68), and 2010 2013 (N = 90) in Navajo Nation. Denominators were based on the active Indian Health Service user population for eligible health care facilities. Prevalence (per 100 000) and period-specific incidence rates (per 100 000 person-years) were computed for youth aged 10 to 19 years. Changes in prevalence were tested with a two-sided skew-corrected inverted score test, while changes in incidence were tested with Poisson regression. RESULTS: YT2D prevalence was high but stable in 2001 and 2009, overall [146.6 (116.8, 184.0) vs 141.5 (112.0, 178.8), P = .65) and in all subgroups. In contrast, incidence rates increased particularly between the second and third periods overall and in most subgroups by age and by sex. CONCLUSIONS: These data confirm the high burden of YT2D among Navajo youth and suggest an increasing risk in more recent years. However, recent improvements in obesity reduction in this population demonstrate optimism for potential reductions in YT2D in Navajo Nation.
AIM: SEARCH has recently reported that both prevalence and incidence of youth onset type 2 diabetes (YT2D) increased among most US race/ethnic groups in the early 2000s. This study reports on the incidence (2002-2013) and prevalence (2001, 2009) of YT2D in the Navajo Nation among youth age < 20 years from 2001 to 2013. METHODS: SEARCH sought to identify prevalent YT2D cases in 2001 (N = 75) and 2009 (N = 70) and all incident YT2D cases in three periods: 2002 to 2005 (N = 53), 2006 to 2009 (N = 68), and 2010 2013 (N = 90) in Navajo Nation. Denominators were based on the active Indian Health Service user population for eligible health care facilities. Prevalence (per 100 000) and period-specific incidence rates (per 100 000 person-years) were computed for youth aged 10 to 19 years. Changes in prevalence were tested with a two-sided skew-corrected inverted score test, while changes in incidence were tested with Poisson regression. RESULTS: YT2D prevalence was high but stable in 2001 and 2009, overall [146.6 (116.8, 184.0) vs 141.5 (112.0, 178.8), P = .65) and in all subgroups. In contrast, incidence rates increased particularly between the second and third periods overall and in most subgroups by age and by sex. CONCLUSIONS: These data confirm the high burden of YT2D among Navajo youth and suggest an increasing risk in more recent years. However, recent improvements in obesity reduction in this population demonstrate optimism for potential reductions in YT2D in Navajo Nation.
Authors: K A Sauder; D Dabelea; R Bailey-Callahan; S Kanott Lambert; J Powell; R James; C Percy; B F Jenks; L Testaverde; J M Thomas; R Barber; J Smiley; C W Hockett; V W Zhong; L Letourneau; K Moore; A M Delamater; E Mayer-Davis Journal: Pediatr Obes Date: 2017-06-21 Impact factor: 4.000
Authors: Elizabeth J Mayer-Davis; Jean M Lawrence; Dana Dabelea; Jasmin Divers; Scott Isom; Lawrence Dolan; Giuseppina Imperatore; Barbara Linder; Santica Marcovina; David J Pettitt; Catherine Pihoker; Sharon Saydah; Lynne Wagenknecht Journal: N Engl J Med Date: 2017-04-13 Impact factor: 91.245
Authors: Dana Dabelea; Joquetta DeGroat; Carmelita Sorrelman; Martia Glass; Christopher A Percy; Charlene Avery; Diana Hu; Ralph B D'Agostino; Jennifer Beyer; Giuseppina Imperatore; Lisa Testaverde; Georgeanna Klingensmith; Richard F Hamman Journal: Diabetes Care Date: 2009-03 Impact factor: 19.112
Authors: Amber Trujillo Lalla; Carmen George; Carolyn Bancroft; Tierra Edison; Audrey Ricks; Kayla Tabb; Sharon Sandman; Shine K Salt; Cameron Curley; Hendrik Dirk de Heer; Caleigh A Curley; Del Yazzie; Sonya Sunhi Shin Journal: Curr Dev Nutr Date: 2022-03-23
Authors: Del Yazzie; Kristen Tallis; Caleigh Curley; Priscilla R Sanderson; Regina Eddie; Sonya Shin; Timothy K Behrens; Carmen George; Ramona Antone-Nez; Shirleen Jumbo-Rintila; Gloria Ann Begay; Hendrik Dirk de Heer Journal: J Public Health Manag Pract Date: 2022 Mar-Apr 01
Authors: Carmen George; Carolyn Bancroft; Shine Salt; Caleigh Curley; Cameron Curley; Regina Eddie; Tierra Edison; Hendrik de Heer; Priscilla R Sanderson; Del Yazzie; Ramona Antone-Nez; Sonya Shin Journal: Prev Med Rep Date: 2021-09-30
Authors: Carmen George; Carolyn Bancroft; Shine Krystal Salt; Cameron S Curley; Caleigh Curley; Hendrik Dirk de Heer; Del Yazzie; Regina Eddie; Ramona Antone-Nez; Sonya Sunhi Shin Journal: PLoS One Date: 2021-09-02 Impact factor: 3.240