Literature DB >> 31259853

Lack of Association Between the S83I ParC Mutation in Mycoplasma genitalium and Treatment Outcomes Among Men Who Have Sex With Men with Nongonococcal Urethritis.

Laura C Chambers1, Jørgen S Jensen2, Jennifer L Morgan3, M Sylvan Lowens3, Sarah S Romano1, Patricia A Totten4,5, Olusegun O Soge4,5, James P Hughes6, Matthew R Golden1,3,4, Lisa E Manhart1,5.   

Abstract

From February 2015 to October 2017, among 20 men who have sex with men with Mycoplasma genitalium-associated nongonococcal urethritis, 15% had macrolide resistance and S83I ParC mutations. Azithromycin followed by moxifloxacin cleared Mycoplasma genitalium in 2 of 2 with and 11 of 13 without S83I mutations. Dual failures were cleared after doxycycline. S83I mutations were not associated with moxifloxacin failure.

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Year:  2019        PMID： 31259853      PMCID： PMC7011110          DOI： 10.1097/OLQ.0000000000001035

Source DB:  PubMed          Journal:  Sex Transm Dis        ISSN： 0148-5717            Impact factor:   2.830


  29 in total

1.  Analysis of the gyrA and parC genes of Mycoplasma genitalium detected in first-pass urine of men with non-gonococcal urethritis before and after fluoroquinolone treatment.

Authors:  T Deguchi; S Maeda; M Tamaki; T Yoshida; H Ishiko; M Ito; S Yokoi; Y Takahashi; S Ishihara
Journal:  J Antimicrob Chemother       Date:  2001-11       Impact factor: 5.790

2.  Mycoplasma genitalium Macrolide and Fluoroquinolone Resistance: Prevalence and Risk Factors Among a 2013-2014 Cohort of Patients in Barcelona, Spain.

Authors:  María-Jesús Barberá; Miguel Fernández-Huerta; Jørgen-Skov Jensen; Estrella Caballero; Antonia Andreu
Journal:  Sex Transm Dis       Date:  2017-08       Impact factor: 2.830

Review 3.  Mycoplasma genitalium: from Chrysalis to multicolored butterfly.

Authors:  David Taylor-Robinson; Jørgen Skov Jensen
Journal:  Clin Microbiol Rev       Date:  2011-07       Impact factor: 26.132

4.  Prevalence, Macrolide Resistance, and Fluoroquinolone Resistance in Mycoplasma genitalium in Men Who Have Sex With Men Attending an Sexually Transmitted Disease Clinic in Dublin, Ireland in 2017-2018.

Authors:  Vanessa Mulligan; Yvonne Lynagh; Susan Clarke; Magnus Unemo; Brendan Crowley
Journal:  Sex Transm Dis       Date:  2019-04       Impact factor: 2.830

5.  Macrolide and fluoroquinolone resistance in Mycoplasma genitalium in two Swedish counties, 2011-2015.

Authors:  Ronza Hadad; Daniel Golparian; Amaya C Lagos; Johan Ljungberg; Peter Nilsson; Jörgen S Jensen; Hans Fredlund; Magnus Unemo
Journal:  APMIS       Date:  2017-12-13       Impact factor: 3.205

6.  Mycoplasma genitalium Antibiotic Resistance-Mediating Mutations in Canadian Women With or Without Chlamydia Trachomatis Infection.

Authors:  Max A Chernesky; Dan Jang; Irene Martin; Linda M N Hoang; Prenilla Naidu; Paul N Levett; John Wylie; Anu Rebbapragada; Sam Ratnam; Marek Smieja; Barbara Weinbaum; Damon Getman
Journal:  Sex Transm Dis       Date:  2017-07       Impact factor: 2.830

7.  Macrolide resistance and azithromycin failure in a Mycoplasma genitalium-infected cohort and response of azithromycin failures to alternative antibiotic regimens.

Authors:  Melanie Bissessor; Sepehr N Tabrizi; Jimmy Twin; Houda Abdo; Christopher K Fairley; Marcus Y Chen; Lenka A Vodstrcil; Jorgen S Jensen; Jane S Hocking; Suzanne M Garland; Catriona S Bradshaw
Journal:  Clin Infect Dis       Date:  2014-12-23       Impact factor: 9.079

8.  Mycoplasma genitalium testing pattern and macrolide resistance: a Danish nationwide retrospective survey.

Authors:  Kirsten Salado-Rasmussen; Jørgen Skov Jensen
Journal:  Clin Infect Dis       Date:  2014-04-11       Impact factor: 9.079

9.  Macrolide resistance in Mycoplasma genitalium from female sex workers in Belgium.

Authors:  Liselotte Coorevits; Ans Traen; Luk Bingé; Patrick Descheemaeker; Jerina Boelens; Marijke Reynders; Elizaveta Padalko
Journal:  J Glob Antimicrob Resist       Date:  2017-10-05       Impact factor: 4.035

10.  Mutations in ParC and GyrA of moxifloxacin-resistant and susceptible Mycoplasma genitalium strains.

Authors:  Ryoichi Hamasuna; Phuong Thi Le; Satoshi Kutsuna; Keiichi Furubayashi; Masahiro Matsumoto; Norio Ohmagari; Naohiro Fujimoto; Tetsuro Matsumoto; Jorgen Skov Jensen
Journal:  PLoS One       Date:  2018-06-08       Impact factor: 3.240
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  2 in total

1.  High Rates of Asymptomatic Mycoplasma genitalium Infections With High Proportion of Genotypic Resistance to First-Line Macrolide Treatment Among Men Who Have Sex With Men Enrolled in the Zurich Primary HIV Infection Study.

Authors:  Alexander Ring; Suraj Balakrishna; Frank Imkamp; Sara Burkard; Flurina Triet; Flurina Brunschweiler; Christina Grube; Rebecca Bodmer; Roger D Kouyos; Huldrych F Günthard; Dominique L Braun
Journal:  Open Forum Infect Dis       Date:  2022-04-27       Impact factor: 4.423

2.  Prevalence and antibiotic resistance of rectal Mollicutes in HIV-infected men who have sex with men at the University Hospital of Dresden, Germany.

Authors:  Petra Spornraft-Ragaller; Roger Dumke
Journal:  Infection       Date:  2020-01-28       Impact factor: 3.553
  2 in total

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