Literature DB >> 31259624

IL-6Ra in Smooth Muscle Cells Protects against Schistosoma- and Hypoxia-induced Pulmonary Hypertension.

Claudia Mickael1, Rahul Kumar1, Daniel Hernandez-Saavedra1, Biruk Kassa1, Linda Sanders1, Dan Koyanagi1, Sue Gu1, Michael H Lee1, Rubin M Tuder1, Brian B Graham1.   

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Year:  2019        PMID： 31259624      PMCID： PMC6604223          DOI： 10.1165/rcmb.2018-0277LE

Source DB:  PubMed          Journal:  Am J Respir Cell Mol Biol        ISSN： 1044-1549            Impact factor:   6.914


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  15 in total

1.  Cell-type specific regulation of thrombospondin-1 expression and its promoter activity by regulatory agents.

Authors:  S A Kim; J H Kang; I Cho; S W Bae; K J Hong
Journal:  Exp Mol Med       Date:  2001-09-30       Impact factor: 8.718

2.  Ectopic upregulation of membrane-bound IL6R drives vascular remodeling in pulmonary arterial hypertension.

Authors:  Yuichi Tamura; Carole Phan; Ly Tu; Morane Le Hiress; Raphaël Thuillet; Etienne-Marie Jutant; Elie Fadel; Laurent Savale; Alice Huertas; Marc Humbert; Christophe Guignabert
Journal:  J Clin Invest       Date:  2018-04-09       Impact factor: 14.808

3.  The Causal Role of IL-4 and IL-13 in Schistosoma mansoni Pulmonary Hypertension.

Authors:  Rahul Kumar; Claudia Mickael; Jacob Chabon; Liya Gebreab; Alleluiah Rutebemberwa; Alexandra Rodriguez Garcia; Daniel E Koyanagi; Linda Sanders; Aneta Gandjeva; Mark T Kearns; Lea Barthel; William J Janssen; Thais Mauad; Angela Bandeira; Eric Schmidt; Rubin M Tuder; Brian B Graham
Journal:  Am J Respir Crit Care Med       Date:  2015-10-15       Impact factor: 21.405

4.  Novel Insights into Interleukin 6 (IL-6) Cis- and Trans-signaling Pathways by Differentially Manipulating the Assembly of the IL-6 Signaling Complex.

Authors:  Marine Lacroix; François Rousseau; Florence Guilhot; Pauline Malinge; Giovanni Magistrelli; Suzanne Herren; Simon A Jones; Gareth W Jones; Jürgen Scheller; Rami Lissilaa; Marie Kosco-Vilbois; Zoë Johnson; Vanessa Buatois; Walter Ferlin
Journal:  J Biol Chem       Date:  2015-09-11       Impact factor: 5.157

5.  Role for interleukin-6 in COPD-related pulmonary hypertension.

Authors:  Ari Chaouat; Laurent Savale; Christos Chouaid; Ly Tu; Benjamin Sztrymf; Matthieu Canuet; Bernard Maitre; Bruno Housset; Christian Brandt; Philippe Le Corvoisier; Emmanuel Weitzenblum; Saadia Eddahibi; Serge Adnot
Journal:  Chest       Date:  2009-04-06       Impact factor: 9.410

6.  Increased interleukin-1 and interleukin-6 serum concentrations in severe primary pulmonary hypertension.

Authors:  M Humbert; G Monti; F Brenot; O Sitbon; A Portier; L Grangeot-Keros; P Duroux; P Galanaud; G Simonneau; D Emilie
Journal:  Am J Respir Crit Care Med       Date:  1995-05       Impact factor: 21.405

7.  Atheroprotective role of interleukin-6 in diet- and/or pathogen-associated atherosclerosis using an ApoE heterozygote murine model.

Authors:  Monika Madan; Biswadev Bishayi; Michael Hoge; Salomon Amar
Journal:  Atherosclerosis       Date:  2007-04-06       Impact factor: 5.162

8.  TGF-β activation by bone marrow-derived thrombospondin-1 causes Schistosoma- and hypoxia-induced pulmonary hypertension.

Authors:  Rahul Kumar; Claudia Mickael; Biruk Kassa; Liya Gebreab; Jeffrey C Robinson; Daniel E Koyanagi; Linda Sanders; Lea Barthel; Christina Meadows; Daniel Fox; David Irwin; Min Li; B Alexandre McKeon; Suzette Riddle; R Dale Brown; Leslie E Morgan; Christopher M Evans; Daniel Hernandez-Saavedra; Angela Bandeira; James P Maloney; Todd M Bull; William J Janssen; Kurt R Stenmark; Rubin M Tuder; Brian B Graham
Journal:  Nat Commun       Date:  2017-05-30       Impact factor: 14.919

9.  Clinical trial protocol for TRANSFORM-UK: A therapeutic open-label study of tocilizumab in the treatment of pulmonary arterial hypertension.

Authors:  Jules Hernández-Sánchez; Louise Harlow; Colin Church; Sean Gaine; Emily Knightbridge; Kate Bunclark; Dee Gor; Alun Bedding; Nicholas Morrell; Paul Corris; Mark Toshner
Journal:  Pulm Circ       Date:  2017-09-28       Impact factor: 3.017

10.  Impact of interleukin-6 on hypoxia-induced pulmonary hypertension and lung inflammation in mice.

Authors:  Laurent Savale; Ly Tu; Dominique Rideau; Mohamed Izziki; Bernard Maitre; Serge Adnot; Saadia Eddahibi
Journal:  Respir Res       Date:  2009-01-27
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  3 in total

1.  Interleukin-6 mediates neutrophil mobilization from bone marrow in pulmonary hypertension.

Authors:  Stephen Y Chan; Partha Dutta; Jonathan Florentin; Jingsi Zhao; Yi-Yin Tai; Sathish Babu Vasamsetti; Scott P O'Neil; Rahul Kumar; Anagha Arunkumar; Annie Watson; John Sembrat; Grant C Bullock; Linda Sanders; Biruk Kassa; Mauricio Rojas; Brian B Graham
Journal:  Cell Mol Immunol       Date:  2021-01-08       Impact factor: 11.530

Review 2.  Schistosomiasis Pulmonary Arterial Hypertension.

Authors:  Jean Pierre Sibomana; Aloma Campeche; Roberto J Carvalho-Filho; Ricardo Amorim Correa; Helena Duani; Virginia Pacheco Guimaraes; Joan F Hilton; Biruk Kassa; Rahul Kumar; Michael H Lee; Camila M C Loureiro; Sula Mazimba; Claudia Mickael; Rudolf K F Oliveira; Jaquelina S Ota-Arakaki; Camila Farnese Rezende; Luciana C S Silva; Edford Sinkala; Hanan Yusuf Ahmed; Brian B Graham
Journal:  Front Immunol       Date:  2020-12-10       Impact factor: 7.561

3.  HIV and Schistosoma Co-Exposure Leads to Exacerbated Pulmonary Endothelial Remodeling and Dysfunction Associated with Altered Cytokine Landscape.

Authors:  Sandra Medrano-Garcia; Daniel Morales-Cano; Bianca Barreira; Alba Vera-Zambrano; Rahul Kumar; Djuro Kosanovic; Ralph Theo Schermuly; Brian B Graham; Francisco Perez-Vizcaino; Alistair Mathie; Rajkumar Savai; Soni Pullamseti; Ghazwan Butrous; Edgar Fernández-Malavé; Angel Cogolludo
Journal:  Cells       Date:  2022-08-04       Impact factor: 7.666
  3 in total

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