Literature DB >> 31257859

Crystals in the Substantia Nigra.

Adam Heller1, Sheryl S Coffman1.   

Abstract

Crystals of TiO2 and CaO were detected in electron-beam exposed extracts of four substantia nigra specimens of Parkinson's disease donors. A likely precursor of the CaO crystals is inflammatory calcium oxalate dihydrate, decomposing according to CaC2O4·2H2O → CaO + CO↑ + CO2↑ + 2H2O↑. Crystals of hydrated iron oxide, earlier reported residents of the human brain, were also found.

Entities:  

Keywords:  Parkinson’s disease; calcium oxide dihydrate; crystals; iron oxide; substantia nigra; titanium dioxide

Year:  2019        PMID: 31257859     DOI: 10.1021/acschemneuro.9b00318

Source DB:  PubMed          Journal:  ACS Chem Neurosci        ISSN: 1948-7193            Impact factor:   4.418


  1 in total

1.  Potentially Pathogenic Calcium Oxalate Dihydrate and Titanium Dioxide Crystals in the Alzheimer's Disease Entorhinal Cortex.

Authors:  Adam Heller; Sheryl S Coffman; Karalee Jarvis
Journal:  J Alzheimers Dis       Date:  2020       Impact factor: 4.472

  1 in total

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