Literature DB >> 31257192

A Case of Gastric Meningeal Carcinomatosis Involving Bilateral Hearing Loss: The Difference between Clinical Images and Autopsy Findings.

Akari Kimura1, Yoichiro Takahashi1, Kunio Mizutari1, Hironori Tsujimoto2, Kuniaki Nakanishi3, Akihiro Shiotani1.   

Abstract

We describe a rare case of meningeal carcinomatosis (MC) in a 66-year-old man who presented with bilateral deafness and vertigo, initially presumed to be neurofibromatosis type-2. Brain magnetic resonance imaging (MRI) of the patient revealed bilateral gadolinium enhanced masses at the cerebellopontine angle. However, multiple central nervous system symptoms, including loss of consciousness, gradually appeared. He had a history of gastric cancer; therefore, a lumbar puncture was performed. Cytological examination of the cerebrospinal fluid confirmed the presence of adenocarcinoma cells. The general condition of this patient worsened, and he died 46 days after the first onset of hearing loss. An autopsy was performed, and multiple infiltrations of adenocarcinoma cells in the brain were confirmed, though undetected by MRI. The prognosis of MC is extremely poor; therefore, rapid diagnosis is important to prevent mortality. Retrospectively, a lumbar puncture could have been conducted earlier to identify MC, especially in consideration of the clinical history of this patient.

Entities:  

Year:  2019        PMID: 31257192      PMCID: PMC6750794          DOI: 10.5152/iao.2019.6080

Source DB:  PubMed          Journal:  J Int Adv Otol        ISSN: 1308-7649            Impact factor:   1.017


  3 in total

1.  Bilateral Hearing Loss Due to Metastatic Gastric Signet Cell Adenocarcinoma Involving the Internal Auditory Canal and Cerebellopontine Angle.

Authors:  Mohamed Bassiouni; Heidi Olze; Philipp Arens
Journal:  J Int Adv Otol       Date:  2021-01       Impact factor: 1.017

2.  Metastatic Brain Tumor in the Cerebellopontine Angle from Gastric Cancer: A Case Report.

Authors:  Masahiro Uchimura; Mizuki Kambara; Kentaro Hayashi; Haruo Takigawa; Yuichi Anno; Yasuhiko Akiyama
Journal:  Asian J Neurosurg       Date:  2022-06-06

3.  Garcin Syndrome Due to Meningeal Carcinomatosis from Gastric Cancer.

Authors:  Kei Terasaki; Chiemi Mizuno; Shinsaku Fujiishi; Shohei Amioka; Takahiro Nonaka; Junichiro Itani; Yusuke Takahashi; Takahiro Miura; Tomoko Yasufuku; Hirohisa Oya; Takayuki Katayama; Kotaro Okuda; Junko Matsumoto; Yasuhide Mitsumoto; Naoki Sawai; Masayuki Mizuno; Toshihide Shima; Takeshi Okanoue
Journal:  Intern Med       Date:  2020-10-21       Impact factor: 1.271

  3 in total

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