Literature DB >> 31256646

Characterization of opioid consumption and disposal patterns after total knee arthroplasty.

A Premkumar1, F C Lovecchio1, J G Stepan1, P K Sculco1, S A Jerabek1, A Gonzalez Della Valle1, D J Mayman1, A D Pearle1, M M Alexiades1, T J Albert1, M B Cross1, S B Haas1.   

Abstract

AIMS: The aim of this study was to determine the general postoperative opioid consumption and rate of appropriate disposal of excess opioid prescriptions in patients undergoing primary unilateral total knee arthroplasty (TKA). PATIENTS AND METHODS: In total, 112 patients undergoing surgery with one of eight arthroplasty surgeons at a single specialty hospital were prospectively enrolled. Three patients were excluded for undergoing secondary procedures within six weeks. Daily pain levels and opioid consumption, quantity, and disposal patterns for leftover medications were collected for six weeks following surgery using a text-messaging platform.
RESULTS: Overall, 103 of 109 patients (94.5%) completed the daily short message service (SMS) surveys. The mean oral morphine equivalents (OME) consumed during the six weeks post-surgery were 639.6 mg (sd 323.7; 20 to 1616) corresponding to 85.3 tablets of 5 mg oxycodone per patient. A total of 66 patients (64.1%) had stopped taking opioids within six weeks of surgery and had the mean equivalent of 18 oxycodone 5 mg tablets remaining. Only 17 patients (25.7%) appropriately disposed of leftover medications.
CONCLUSION: These prospectively collected data provide a benchmark for general opioid consumption after uncomplicated primary unilateral TKA. Many patients are prescribed more opioids than they require, and leftover medication is infrequently disposed of appropriately, which increases the risk for illicit diversion. Cite this article: Bone Joint J 2019;101-B(7 Supple C):98-103.

Entities:  

Keywords:  Opioid consumption; Opioid disposal; Total knee arthroplasty

Mesh:

Substances:

Year:  2019        PMID: 31256646     DOI: 10.1302/0301-620X.101B7.BJJ-2018-1518.R1

Source DB:  PubMed          Journal:  Bone Joint J        ISSN: 2049-4394            Impact factor:   5.082


  8 in total

1.  The Ramifications of Opioid Utilization and Outcomes of Alternative Pain Control Strategies for Total Knee Arthroplasties.

Authors:  Kevin Berardino; Austin H Carroll; Robert Ricotti; Daniel Popovsky; Matthew D Civilette; Ivan Urits; Omar Viswanath; William F Sherman; Alan D Kaye
Journal:  Orthop Rev (Pavia)       Date:  2022-08-30

2.  Inpatient and outpatient opioid requirements after total joint replacement are strongly influenced by patient and surgical factors.

Authors:  Austin J Roebke; Garrhett G Via; Joshua S Everhart; Maria A Munsch; Kanu S Goyal; Andrew H Glassman; Mengnai Li
Journal:  Bone Jt Open       Date:  2020-11-02

3.  Combating the Opioid Epidemic: Experience with a Single Prescription for Total Joint Arthroplasty.

Authors:  Daniel Sun; Antonio Cusano; Melvin A Harrington; Mohamad J Halawi
Journal:  Arthroplast Today       Date:  2020-08-23

Review 4.  The Management of Acute Pain for Musculoskeletal Conditions: The Challenges of Opioids and Opportunities for the Future.

Authors:  Lia D Delaney; Daniel J Clauw; Jennifer F Waljee
Journal:  J Bone Joint Surg Am       Date:  2020-05-20       Impact factor: 6.558

5.  An opioid-sparing protocol with intravenous parecoxib can effectively reduce morphine consumption after simultaneous bilateral total knee arthroplasty.

Authors:  Hsuan-Hsiao Ma; Te-Feng Arthur Chou; Hsin-Yi Wang; Shang-Wen Tsai; Cheng-Fong Chen; Po-Kuei Wu; Wei-Ming Chen
Journal:  Sci Rep       Date:  2021-04-01       Impact factor: 4.379

6.  Older, Male Orthopaedic Surgeons From Southern Geographies Prescribe Higher Doses of Post-Operative Narcotics Than do their Counterparts: A Medicare Population Study.

Authors:  Eric W Guo; Nikhil R Yedulla; Austin G Cross; Luke T Hessburg; Kareem G Elhage; Dylan S Koolmees; Eric C Makhni
Journal:  Arthrosc Sports Med Rehabil       Date:  2021-10-19

7.  The Use of Opioids and Pain Medications in the Management of Postoperative Pain in Total Knee Arthroplasty Patients: A Retrospective Study.

Authors:  Ammar Almustafa; Asdghig Der-Boghossian; Abdel Majid Sheikh Taha
Journal:  Pain Res Manag       Date:  2022-03-29       Impact factor: 3.037

8.  Narcotic Refills and Patient Satisfaction With Pain Control After Total Joint Arthroplasty.

Authors:  Jeffrey B Stambough; Ryan Hui; Eric R Siegel; Paul K Edwards; C Lowry Barnes; Simon C Mears
Journal:  J Arthroplasty       Date:  2020-08-04       Impact factor: 4.757

  8 in total

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