Literature DB >> 312564

The Warren shunt in treating bleeding esophageal varices.

R W Busuttil, B T Maywood, R K Tompkins.   

Abstract

In patients who have impaired hepatic reserve, the Warren shunt has been proposed as an effective operation because it decompresses the esophageal varices without disturbing portal perfusion of the liver. However, early reports of high operative mortality and technical difficulties have impeded acceptance of the procedure. The operation was done in a series of 17 patients. All patients in whom elective variceal decompression with a patent splenic vein was required and without clinical ascites were candidates for this operation. Follow-up ranged from 2 to 48 months. Six patients had alcoholic cirrhosis, two had primary biliary cirrhosis and seven had postnecrotic cirrhosis; in two the cause of the liver disease was unknown. Five patients were categorized as Child's class A, nine as class B and three as class C. No intraoperative or early postoperative deaths owing to hemorrhage occurred. However, there was one death two weeks postoperatively from pulmonary sepsis and one death five weeks postoperatively due to antigen-positive hepatitis. Two patients died from hepatic failure six weeks and five months after operation, respectively; in the first of these, chronic active hepatitis was diagnosed at the time of operation. In one patient hemorrhage recurred and transfusion was required. Although ascites, which eventually resolved, developed in eight patients after operation, the results in 76 percent of patients have been good without new episodes of hemorrhage or encephalopathy. We conclude that the Warren shunt is a safe and effective elective operation for the treatment of patients in whom hemorrhage from esophageal varices has occurred.

Entities:  

Mesh:

Year:  1979        PMID: 312564      PMCID: PMC1238617     

Source DB:  PubMed          Journal:  West J Med        ISSN: 0093-0415


  12 in total

1.  Results of left gastric vena caval shunt for esophageal varices: Analysis of one hundred clinical cases.

Authors:  K Inokuchi; M Kobayashi; Y Ogawa; M Saku; N Nagasue
Journal:  Surgery       Date:  1975-11       Impact factor: 3.982

2.  The fate of esophageal varices following selective distal splenorenal shunt.

Authors:  D G Hutson; R Pereiras; R Zeppa; J U Levi; E R Schiff; P Fink
Journal:  Ann Surg       Date:  1976-05       Impact factor: 12.969

3.  A series of 20 successful Warren shunts.

Authors:  N R Thomford; K R Sirinek; E W Martin
Journal:  Arch Surg       Date:  1975-05

4.  Selective distal splenorenal shunt. Technique and results of operation.

Authors:  W D Warren; A A Salam; D Hutson; R Zeppa
Journal:  Arch Surg       Date:  1974-03

5.  Therapeutic portacaval shunt. Preliminary data on controlled trial and morbid effects of acute hyaline necrosis.

Authors:  W P Mikkelsen
Journal:  Arch Surg       Date:  1974-03

6.  A controlled study of the therapeutic portacaval shunt.

Authors:  R H Resnick; F L Iber; A M Ishihara; T C Chalmers; H Zimmerman
Journal:  Gastroenterology       Date:  1974-11       Impact factor: 22.682

7.  The metabolic basis of portasystemic encephalopathy and the effect of selective vs nonselective shunts.

Authors:  W D Warren; D Rudman; W Millikan; J T Galambos; A A Salam; R B Smith
Journal:  Ann Surg       Date:  1974-10       Impact factor: 12.969

8.  A clinical investigation of the portacaval shunt. V. Survival analysis of the therapeutic operation.

Authors:  F C Jackson; E B Perrin; W R Felix; A G Smith
Journal:  Ann Surg       Date:  1971-10       Impact factor: 12.969

9.  A controlled study of therapeutic portacaval shunt in alcoholic cirrhosis.

Authors:  B Rueff; D Prandi; F Degos; J Sicot; J D Degos; C Sicot; J N Maillard; R Fauvert; J P Benhamou
Journal:  Lancet       Date:  1976-03-27       Impact factor: 79.321

10.  Recurrent variceal hemorrhage following successful Warren shunt.

Authors:  R E Carlson; W K Ehrenfeld
Journal:  Arch Surg       Date:  1976-05
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