Literature DB >> 3125081

Pathogenetic heterogeneity in retinal capillary basement membrane thickening in the diabetic BB-rat.

S Chakrabarti1, A A Sima.   

Abstract

In the present study, we compared the effects of good blood glucose control and that of aldose reductase inhibitor (Statil) treatment on diabetic retinal capillary basement membrane thickening in the diabetic BB-rat. Aggressive insulin treatment maintaining euglycaemia for 4 months prevented the characteristic basement membrane thickening in both the superficial and deep capillary beds of the diabetic retina. Statil treatment of hyperglycaemic rats for the same length of time prevented basement membrane thickening in the deep capillary bed but not in the superficial capillaries.

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Year:  1987        PMID： 3125081     DOI： 10.1007/bf00295883

Source DB:  PubMed          Journal:  Diabetologia        ISSN： 0012-186X            Impact factor:   10.122


  9 in total

1.  Prevention of basement membrane thickening in retinal capillaries by a novel inhibitor of aldose reductase, tolrestat.

Authors:  W G Robison; P F Kador; Y Akagi; J H Kinoshita; R Gonzalez; D Dvornik
Journal:  Diabetes       Date:  1986-03       Impact factor: 9.461

2.  Regional variations in the width of the basement membrane of muscle capillaries in man and giraffe.

Authors:  J R Williamson; N J Vogler; C Kilo
Journal:  Am J Pathol       Date:  1971-05       Impact factor: 4.307

3.  A rapid reproducible method for determination of basement membrane thickness in biological structures.

Authors:  T A McEwen; S Chakrabarti; A A Sima
Journal:  Comput Biol Med       Date:  1987       Impact factor: 4.589

4.  Structure of basement membrane in normal and diabetic tissue.

Authors:  D H Rohrbach; G R Martin
Journal:  Ann N Y Acad Sci       Date:  1982       Impact factor: 5.691

5.  Diabetic autonomic neuropathy. The distribution of structural changes in sympathetic nerves of the BB rat.

Authors:  S Yagihashi; A A Sima
Journal:  Am J Pathol       Date:  1985-10       Impact factor: 4.307

6.  The effects of long-term treatment of streptozotocin-diabetic rats with an aldose reductase inhibitor.

Authors:  R Poulsom; R P Boot-Handford; H Heath
Journal:  Exp Eye Res       Date:  1983-11       Impact factor: 3.467

7.  Retinal capillaries: basement membrane thickening by galactosemia prevented with aldose reductase inhibitor.

Authors:  W G Robison; P F Kador; J H Kinoshita
Journal:  Science       Date:  1983-09-16       Impact factor: 47.728

8.  Galactose-induced retinal capillary basement membrane thickening: prevention by Sorbinil.

Authors:  R N Frank; R J Keirn; A Kennedy; K W Frank
Journal:  Invest Ophthalmol Vis Sci       Date:  1983-11       Impact factor: 4.799

9.  On the pathogenesis of diabetic retinopathy.

Authors:  R N Frank
Journal:  Ophthalmology       Date:  1984-06       Impact factor: 12.079
  9 in total
  4 in total

1.  Impaired visual evoked potential and primary axonopathy of the optic nerve in the diabetic BB/W-rat.

Authors:  A A Sima; W X Zhang; P V Cherian; S Chakrabarti
Journal:  Diabetologia       Date:  1992-07       Impact factor: 10.122

2.  Diabetic eNOS-knockout mice develop accelerated retinopathy.

Authors:  Qiuhong Li; Amrisha Verma; Ping-Yang Han; Takahiko Nakagawa; Richard J Johnson; Maria B Grant; Martha Campbell-Thompson; Yagna P R Jarajapu; Bo Lei; William W Hauswirth
Journal:  Invest Ophthalmol Vis Sci       Date:  2010-04-30       Impact factor: 4.799

3.  Reduced number of anionic sites is associated with glomerular basement membrane thickening in the diabetic BB-rat.

Authors:  S Chakrabarti; N Ma; A A Sima
Journal:  Diabetologia       Date:  1989-11       Impact factor: 10.122

4.  Effects of aldose reductase inhibition with tolrestat on diabetic retinopathy in a six months double blind trial.

Authors:  J M van Gerven; J P Boot; H H Lemkes; J A van Best
Journal:  Doc Ophthalmol       Date:  1994       Impact factor: 2.379
  4 in total

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