A Facile Approach for On-Site Evaluation of Nicotine in Tobacco and Environmental Tobacco Smoke.

Nicotine is highly addictive and harmful. It is one of the main active ingredients in tobacco and a major pollutant in environmental tobacco smoke. Thus, it is important to detect the nicotine content in tobacco and to monitor the nicotine content in environmental tobacco smoke. However, until present, there still has been no effective device for on-site determination of nicotine content in tobacco and environmental tobacco smoke. In this work, a portable device is fabricated for sensitive on-site evaluation of nicotine in tobacco and environmental tobacco smoke based on surface-enhanced Raman scattering (SERS). The weight of the entire device is less than 1 kg, and it uses a chargeable battery to drive both the pump and the Raman spectrometer. The total analysis time can be completed within 3-5 min. Thus, it has great potential for on-site analysis of nicotine in tobacco and environmental tobacco smoke.