BACKGROUND: Despite the widespread adoption of the transradial approach for elderly patients undergoing percutaneous coronary intervention (PCI) in clinical practice, data on octogenarians in China are still relatively limited. This study sought to compare both the safety and efficacy of transradial intervention (TRI) and transfemoral intervention (TFI) in octogenarians in China. METHODS: We identified 254 octogenarians who underwent PCIs in Fuwai Hospital, Beijing, China between January 1, 2006 and April 30, 2011. TRI was used in 184 patients and TFI was used in 70 patients. Incidence rates of in- hospital and 1-year clinical outcomes were compared between the two groups. Ono-to-one propensity score matching (PSM) was performed to control for potential bias. A total of 48 pairs were matched. RESULTS: Baseline and procedural characteristics were balanced between the TRI and TFI groups. Patients undergoing TRI had significantly fewer access site complications (10.3% vs. 20.0%, p = 0.040), although this difference did not remain significant in propensity score-matched patients (10.4% vs. 22.9%, p = 0.100). After PSM, the patients undergoing TRI were less likely to have major post-PCI bleeding (0 vs. 12.5%, odds ratio 0.47, 95% confidence interval 0.37-0.58, p = 0.026). There were no statistical differences in the incidence rates of major adverse cardiac events (a composite of cardiac death, myocardial infarction, and target vessel revascularization) and their components both during hospitalization and at 1-year. CONCLUSIONS: Compared with TFI, TRI was safer and more feasible for octogenarians undergoing PCI.
BACKGROUND: Despite the widespread adoption of the transradial approach for elderly patients undergoing percutaneous coronary intervention (PCI) in clinical practice, data on octogenarians in China are still relatively limited. This study sought to compare both the safety and efficacy of transradial intervention (TRI) and transfemoral intervention (TFI) in octogenarians in China. METHODS: We identified 254 octogenarians who underwent PCIs in Fuwai Hospital, Beijing, China between January 1, 2006 and April 30, 2011. TRI was used in 184 patients and TFI was used in 70 patients. Incidence rates of in- hospital and 1-year clinical outcomes were compared between the two groups. Ono-to-one propensity score matching (PSM) was performed to control for potential bias. A total of 48 pairs were matched. RESULTS: Baseline and procedural characteristics were balanced between the TRI and TFI groups. Patients undergoing TRI had significantly fewer access site complications (10.3% vs. 20.0%, p = 0.040), although this difference did not remain significant in propensity score-matched patients (10.4% vs. 22.9%, p = 0.100). After PSM, the patients undergoing TRI were less likely to have major post-PCI bleeding (0 vs. 12.5%, odds ratio 0.47, 95% confidence interval 0.37-0.58, p = 0.026). There were no statistical differences in the incidence rates of major adverse cardiac events (a composite of cardiac death, myocardial infarction, and target vessel revascularization) and their components both during hospitalization and at 1-year. CONCLUSIONS: Compared with TFI, TRI was safer and more feasible for octogenarians undergoing PCI.
Authors: Yoshio Kobayashi; Roxana Mehran; Gary S Mintz; George Dangas; Issam Moussa; Alexandra J Lansky; Gregg W Stone; Jeffrey W Moses; Martin B Leon Journal: Am J Cardiol Date: 2003-08-15 Impact factor: 2.778
Authors: Dmitriy N Feldman; Christopher L Gade; Alexander J Slotwiner; Manish Parikh; Geoffrey Bergman; S Chiu Wong; Robert M Minutello Journal: Am J Cardiol Date: 2006-09-28 Impact factor: 2.778
Authors: Lloyd W Klein; Peter Block; Ralph G Brindis; Charles R McKay; Ben D McCallister; Michael Wolk; William Weintraub Journal: J Am Coll Cardiol Date: 2002-08-07 Impact factor: 24.094
Authors: Abid R Assali; Ali Moustapha; Stefano Sdringola; Joseph Salloum; Hany Awadalla; Sangeeta Saikia; Mohammad Ghani; Susan Hale; G Schroth; Oscar Rosales; H Vernon Anderson; Richard W Smalling Journal: Catheter Cardiovasc Interv Date: 2003-06 Impact factor: 2.692
Authors: Winthrop D Piper; David J Malenka; Thomas J Ryan; Samuel J Shubrooks; Gerald T O'Connor; John F Robb; Karen L Farrell; Mary S Corliss; Michael J Hearne; Mirle A Kellett; Matthew W Watkins; William A Bradley; Bruce D Hettleman; Theodore M Silver; Paul D McGrath; John R O'Mears; David E Wennberg Journal: Am Heart J Date: 2003-06 Impact factor: 4.749