| Literature DB >> 31248657 |
Gulimire Naizhaer1, Ayixibuwei Kuerban2, Reziya Kuerban3, Ping Zhou4.
Abstract
We examined the expression level of focally amplified lncRNA on chromosome 1 (FALEC) in cervical cancer patients and explore its clinical value in diagnosis and prognosis of cervical cancer. FALEC was significantly up-regulated in the blood plasma from cervical cancer patients and had significant correlation with tumor size, the FIGO stage, and lymph node metastasis. Furthermore, FALEC overexpression could stimulate proliferation and invasion of Hela cells. FALEC was a potential molecular marker used to diagnose cervical cancer and evaluate prognosis.Entities:
Keywords: Cell proliferation; Cervical cancer; Focally amplified lncRNA on chromosome 1; Long noncoding RNA; Prognosis biomarker
Year: 2019 PMID： 31248657 DOI： 10.1016/j.prp.2019.152495
Source DB: PubMed Journal: Pathol Res Pract ISSN： 0344-0338 Impact factor: 3.250