| Literature DB >> 3124844 |
A Hasegawa1, H Yamashita, S Kondo, T Kiyota, H Hayashi, H Yoshizaki, A Murakami, M Shiratsuchi, T Mori.
Abstract
Proteose peptone markedly enhanced the production of human tissue-type plasminogen activator (t-PA) from confluently cultured cell of human diploid fibroblasts. The cells continued synthesizing and secreting high levels of t-PA under periodic replacement of medium containing proteose peptone for more than one month. The highly increased activity correlated with equally increased levels of t-PA antigen and concomitantly increased levels of t-PA specific mRNA.Entities:
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Year: 1988 PMID： 3124844 DOI： 10.1016/0006-291x(88)90760-7
Source DB: PubMed Journal: Biochem Biophys Res Commun ISSN： 0006-291X Impact factor: 3.575