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Literature DB >> 3124815

Platelet-reactive sites in collagen. Collagens I and III possess different aggregatory sites.

L F Morton¹, C M Fitzsimmons, J Rauterberg, M J Barnes.

Abstract

Collagen type III possesses a highly reactive platelet-aggregatory site at a locus which in type I is essentially inactive whilst the latter collagen possesses reactive sites absent in type III. It is proposed that platelet aggregation by collagen involves the sequence GK[or R]PG(EY)GPK[or R]G(EY) or, less favourably, GPK[or R]G(EY)G(XY)GK[or R]PG(EY), one basic residue acting in combination with the second in an adjacent alpha-chain.

Entities: Disease Gene

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Year: 1987 PMID： 3124815 PMCID： PMC1148567 DOI： 10.1042/bj2480483

Source DB: PubMed Journal: Biochem J ISSN： 0264-6021 Impact factor: 3.857

22 in total

Review 1. Collagens in atherosclerosis.

Authors: M J Barnes
Journal: Coll Relat Res Date: 1985-01

2. Effect of a collagen derived octapeptide on different steps of the platelet/collagen interaction.

Authors: A Karniguian; Y J Legrand; P Lefrancier; J P Caen
Journal: Thromb Res Date: 1983-12-15 Impact factor: 3.944

3. The platelet reactivity of the alpha 2(I)-chain of type I collagen: platelet aggregation induced by polymers of the molecule [alpha 2(I)]3.

Authors: C M Fitzsimmons; M J Barnes
Journal: Thromb Res Date: 1985-08-15 Impact factor: 3.944

4. Reevaluation of the role of the polar groups of collagen in the platelet-collagen interaction.

Authors: C M Chesney; D D Pifer; L J Crofford; K M Huch
Journal: Am J Pathol Date: 1983-08 Impact factor: 4.307

5. The interaction between collagens and factor VIII/von Willebrand factor: investigation of the structural requirements for interaction.

Authors: L F Morton; B Griffin; D S Pepper; M J Barnes
Journal: Thromb Res Date: 1983-12-15 Impact factor: 3.944

6. The covalent structure of calf skin type III collagen. III. The amino acid sequence of the cyanogen bromide peptide alpha 1(III)CB4 (positions 403--551).

Authors: H Bentz; P P Fietzek; K Kühn
Journal: Hoppe Seylers Z Physiol Chem Date: 1979-07

7. Platelet adhesion to type III collagen : involvement of a sequence of nine aminoacids from alpha 1 (III) CB peptide.

Authors: F Fauvel; Y J Legrand; K Kühn; H Bentz; P P Fietzek; J P Caen
Journal: Thromb Res Date: 1979 Impact factor: 3.944

8. Thrombosis and acute coronary-artery lesions in sudden cardiac ischemic death.

Authors: M J Davies; A Thomas
Journal: N Engl J Med Date: 1984-05-03 Impact factor: 91.245

9. Inhibition of platelet adhesion to fibronectin, fibrinogen, and von Willebrand factor substrates by a synthetic tetrapeptide derived from the cell-binding domain of fibronectin.

Authors: D M Haverstick; J F Cowan; K M Yamada; S A Santoro
Journal: Blood Date: 1985-10 Impact factor: 22.113

10. Collagen-mediated platelet aggregation: the role of multiple interactions between the platelet surface and collagen.

Authors: S A Santoro; L W Cunningham
Journal: Thromb Haemost Date: 1980-06-18 Impact factor: 5.249

5 in total

1. Identification of the epitope for a monoclonal antibody that blocks platelet aggregation induced by type III collagen.

Authors: V Glattauer; J A Werkmeister; A Kirkpatrick; J A Ramshaw
Journal: Biochem J Date: 1997-04-01 Impact factor: 3.857

5. Integrin alpha 2 beta 1-independent activation of platelets by simple collagen-like peptides: collagen tertiary (triple-helical) and quaternary (polymeric) structures are sufficient alone for alpha 2 beta 1-independent platelet reactivity.

Authors: L F Morton; P G Hargreaves; R W Farndale; R D Young; M J Barnes
Journal: Biochem J Date: 1995-03-01 Impact factor: 3.857