Literature DB >> 31247797

Cu-Catalyzed Cross-Dehydrogenative Coupling of Heteroaryl C(sp2)-H and Tertiary C(sp3)-H Bonds for the Construction of All-Carbon Triaryl Quaternary Centers.

Zhi Tang1, Zhili Liu1, Zhou Tong1, Zhihui Xu1, Chak-Tong Au1,2, Renhua Qiu1, Nobuaki Kambe1,3.   

Abstract

A Cu-catalyzed protocol for cross-dehydrogenative coupling of benzofuranones with quinolines, indoles, carbazoles, and thiophene, which furnishes highly functionalized 3,3-diaryl benzofuranones bearing a three aryl quaternary carbon center at the C3 position in good yields, has been developed. A radical mechanism is proposed.

Entities:  

Year:  2019        PMID： 31247797     DOI： 10.1021/acs.orglett.9b01755

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  3 in total

1.  Copper Catalyzed Oxidative Arylation of Tertiary Carbon Centers.

Authors:  Prakash Basnet; Melissa B Sebold; Charles E Hendrick; Marisa C Kozlowski
Journal:  Org Lett       Date:  2020-12-02       Impact factor: 6.005

2.  One-Pot Three-Component Coupling Reaction of α-Amino Aryl Ketones, Indoles, and Perbromomethane Under Mild Conditions.

Authors:  Hao Lu; Yuxuan Liu; Wei Deng; Renhua Qiu; Jiannan Xiang
Journal:  Front Chem       Date:  2022-02-04       Impact factor: 5.221

3.  Improved Method for Preparation of 3-(1H-Indol-3-yl)benzofuran-2(3H)-ones.

Authors:  Igor Yu Grishin; Nikolai A Arutiunov; Dmitrii A Aksenov; Nicolai A Aksenov; Alexander V Aksenov; Amina Z Gasanova; Elena A Sorokina; Carolyn Lower; Michael Rubin
Journal:  Molecules       Date:  2022-03-15       Impact factor: 4.411
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.