Novel odor-based strategies for integrated management of vectors of disease.

The proven ability of vector mosquitoes to adapt to various strategies developed to control them has enabled mosquito-borne diseases such as malaria, dengue, and lymphatic filariasis to remain entrenched as public health threats all over the world. Rather than continuing to seek a miracle cure for all mosquito vector problems among the ranks of single mode-of-action chemical pesticides, today's developers of vector control strategies are increasingly turning to more integrated, varied techniques, relying on pheromones and other semiochemicals to effect vector control through behavioral manipulation of the vector. Examples of this focus include attract-and-kill technologies utilizing floral odors and vertebrate host-associated scent cues to achieve control of adult mosquitoes, and selective oviposition attractants and larval phagostimulants to improve the efficacy of bacterial larvicides.