Literature DB >> 31244458

Infection prevention and control practices related to carbapenemase-producing Enterobacteriaceae (CPE) in acute-care hospitals in Ontario, Canada.

Alainna J Jamal1, Felipe Garcia-Jeldes2, Mahin Baqi3, Sergio Borgia3, Jennie Johnstone2, Kevin Katz4, Philipp Kohler2, Matthew P Muller1, Allison J McGeer1.   

Abstract

OBJECTIVE: To determine infection prevention and control (IPAC) practices for carbapenemase-producing Enterobacteriaceae (CPE), an emerging threat, at acute-care hospitals in Ontario, Canada.
DESIGN: A descriptive cross-sectional survey.
METHODS: We surveyed IPAC directors and managers at all acute-care hospitals in Ontario, Canada, to gather information on IPAC practices related to CPE, including admission screening, other patient screening, environmental testing, use of precautions to prevent transmission, and outbreak management.
RESULTS: Of 116 acute-care hospitals, 105 (91%) responded. Admission screening included patients previously colonized or infected with CPE (n = 64, 61%), patients recently hospitalized outside of Canada (Indian subcontinent, n = 62, 59%; other countries, n = 56, 53%), and patients recently hospitalized in Canada (n = 22, 21%). Fifty-one hospitals (49%) screened patients for colonization during an outbreak. Almost all hospitals (n = 101, 96%) used precautions to prevent transmission from patients with CPE colonization or infection; most hospitals (n = 54, 53%) continued precautions indefinitely. Few hospitals (n = 19, 18%) performed environmental cultures. Eight hospitals (8%) reported at least 1 outbreak, and 6 hospitals (6%) reported transmission from sink or shower drains to patients.
CONCLUSIONS: Variability in practices may result from lack of evidence and challenges in updating guidelines as evidence emerges. A coordinated approach to slow the emergence of CPE should be considered in our population.

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Mesh:

Year:  2019        PMID: 31244458     DOI: 10.1017/ice.2019.173

Source DB:  PubMed          Journal:  Infect Control Hosp Epidemiol        ISSN: 0899-823X            Impact factor:   3.254


  8 in total

1.  Household Transmission of Carbapenemase-producing Enterobacterales in Ontario, Canada.

Authors:  Alainna J Jamal; Amna Faheem; Lubna Farooqi; Xi Zoe Zhong; Irene Armstrong; David A Boyd; Emily Borgundvaag; Brenda L Coleman; Karen Green; Kithsiri Jayasinghe; Jennie Johnstone; Kevin Katz; Philipp Kohler; Angel X Li; Laura Mataseje; Roberto Melano; Matthew P Muller; Michael R Mulvey; Sarah Nayani; Samir N Patel; Aimee Paterson; Susan Poutanen; Anu Rebbapragada; David Richardson; Alicia Sarabia; Shumona Shafinaz; Andrew E Simor; Barbara M Willey; Laura Wisely; Allison J McGeer
Journal:  Clin Infect Dis       Date:  2021-12-06       Impact factor: 9.079

2.  Outbreak of Carbapenemase-Producing Enterobacteriaceae in a Regional Burn Center.

Authors:  Sarah Rehou; Sydney Rotman; Melisa Avaness; Natasha Salt; Marc G Jeschke; Shahriar Shahrokhi
Journal:  J Burn Care Res       Date:  2022-09-01       Impact factor: 1.819

3.  Genomic Epidemiology of Carbapenemase-Producing Enterobacterales at a Hospital System in Toronto, Ontario, Canada, 2007 to 2018.

Authors:  Alainna J Jamal; Laura F Mataseje; Victoria Williams; Jerome A Leis; Nathalie Tijet; Sandra Zittermann; Roberto G Melano; Michael R Mulvey; Kevin Katz; Vanessa G Allen; Allison J McGeer
Journal:  Antimicrob Agents Chemother       Date:  2021-07-16       Impact factor: 5.191

4.  Risk Factors for and Clinical Outcomes of Carbapenem-Resistant Klebsiella pneumoniae Nosocomial Infections: A Retrospective Study in a Tertiary Hospital in Beijing, China.

Authors:  Huijuan Zhang; Zhe Guo; Yan Chai; Yi-Peng Fang; Xiangdong Mu; Nan Xiao; Jun Guo; Zhong Wang
Journal:  Infect Drug Resist       Date:  2021-04-13       Impact factor: 4.003

5.  Rectal and Tracheal Carriage of Carbapenemase Genes and Class 1 and 2 Integrons in Patients in Neurosurgery Intensive Care Unit.

Authors:  Ekaterina S Kuzina; Tatiana S Novikova; Evgeny I Astashkin; Galina N Fedyukina; Angelina A Kislichkina; Natalia V Kurdyumova; Ivan A Savin; Olga N Ershova; Nadezhda K Fursova
Journal:  Antibiotics (Basel)       Date:  2022-07-03

6.  Molecular epidemiology of an extended multiple-species OXA-48 CPE outbreak in a hospital ward in Ireland, 2018-2019.

Authors:  Carina Brehony; Lisa Domegan; Margaret Foley; Margaret Fitzpatrick; Jacqueline P Cafferkey; Karina O'Connell; Binu Dinesh; Eleanor McNamara; Fionnuala Duffy; Fidelma Fitzpatrick; Karen Burns
Journal:  Antimicrob Steward Healthc Epidemiol       Date:  2021-12-08

Review 7.  Neonates with Maternal Colonization of Carbapenemase-Producing, Carbapenem-Resistant Enterobacteriaceae: A Mini-Review and a Suggested Guide for Preventing Neonatal Infection.

Authors:  Judy Seesahai; Paige Terrien Church; Elizabeth Asztalos; Melanee Eng-Chong; Jo Arbus; Rudaina Banihani
Journal:  Children (Basel)       Date:  2021-05-15

8.  Epidemiology and risk factors of rectal colonization of carbapenemase-producing Enterobacteriaceae among high-risk patients from ICU and HSCT wards in a university hospital.

Authors:  Li Yan; Jide Sun; Xiuyu Xu; Shifeng Huang
Journal:  Antimicrob Resist Infect Control       Date:  2020-09-23       Impact factor: 4.887

  8 in total

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