| Literature DB >> 31244412 |
Ana P Francisco1, Eduarda Mendes1, Ana R Santos1, Maria J Perry1.
Abstract
Triazenes are a very useful and diverse class of compounds that have been studied for their potential in the treatment of many tumors including brain tumor, leukemia and melanoma. Novel compounds of this class continue to be developed as either anticancer compounds or even with other therapeutic applications. This review focused on several types of triazenes from the simplest ones like 1,3-dialkyl-3-acyltriazenes to the more complex ones like combi-triazenes with an emphasis on how triazenes have been developed as effective antitumor agents. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.Entities:
Keywords: Triazenes; alkylating agents; anticancer activity; aryltriazenes; combi-triazenes; hybrid molecules; prodrugs.
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Year: 2019 PMID: 31244412 DOI: 10.2174/1381612825666190617155749
Source DB: PubMed Journal: Curr Pharm Des ISSN: 1381-6128 Impact factor: 3.116