| Literature DB >> 31243083 |
Amritha Ramakrishnan1, Nina M Schumack2,3, Christina L Gariepy2,3, Heather Eggleston2,3, Gladys Nunez1, Nereyda Espinoza1, Monica Nieto1, Rosa Castillo1, Jesus Rojas1, Andrea J McCoy1, Zoltan Beck4, Gary R Matyas5, Carl R Alving5, Patricia Guerry3, Frédéric Poly3, Renee M Laird6,3.
Abstract
Entities:
Year: 2019 PMID: 31243083 PMCID: PMC6595154 DOI: 10.1128/mSphere.00440-19
Source DB: PubMed Journal: mSphere ISSN: 2379-5042 Impact factor: 4.389
Protective efficacy of the CPS-CRM vaccine in A. nancymaae NHPs using various adjuvants
| Group | No. of | Diarrhea attack | Protective efficacy | |
|---|---|---|---|---|
| CPS-CRM + alum | 10 | 5 (50) | 29 | 0.43 |
| CPS-CRM + ALF | 17 | 4 (24) | 66 | 0.008 |
| CPS-CRM + ALFQ | 10 | 1 (10) | 86 | 0.005 |
| PBS | 20 | 14 (70) |
Protective efficacy was calculated as follows: [(attack rate of PBS-treated animals − attack rate of vaccinated animals)/attack rate of PBS-treated animals] × 100.
Determined using a Fisher exact test with no adjustment for multiple comparisons.