Literature DB >> 3123918

A complex translocation at the murine kappa light-chain locus.

M A Shapiro1, M Weigert.   

Abstract

We have previously reported that a segment of DNA from a murine plasmacytoma comprises DNA from three chromosomes, the immunoglobulin kappa light-chain locus on chromosome 6, the S mu locus on chromosome 12, and a region on chromosome 15. We now report that the reciprocal product contains DNA from only the kappa locus and chromosome 15 and not from S mu. We conclude that a complex series of events, including both a transposition of DNA and a translocation between chromosomes, generated these imperfect reciprocal products.

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Year:  1987        PMID： 3123918      PMCID： PMC368086          DOI： 10.1128/mcb.7.11.4130-4133.1987

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN： 0270-7306            Impact factor:   4.272


  24 in total

1.  The t(8; 14) chromosomal translocation occurring in B-cell malignancies results from mistakes in V-D-J joining.

Authors:  F G Haluska; S Finver; Y Tsujimoto; C M Croce
Journal:  Nature       Date:  1986 Nov 13-19       Impact factor: 49.962

2.  Repeated gene families in Drosophila melanogaster.

Authors:  D J Finnegan; G M Rubin; M W Young; D S Hogness
Journal:  Cold Spring Harb Symp Quant Biol       Date:  1978

3.  DNA sequence homology and chromosomal deletion at a site of SV40 DNA integration.

Authors:  J R Stringer
Journal:  Nature       Date:  1982-03-25       Impact factor: 49.962

4.  Aberrant rearrangement of the kappa light-chain locus involving the heavy-chain locus and chromosome 15 in a mouse plasmacytoma.

Authors:  B G VanNess; M Shapiro; D E Kelley; R P Perry; M Weigert; P D'Eustachio; F Ruddle
Journal:  Nature       Date:  1983-02-03       Impact factor: 49.962

5.  Role of short regions of homology in intermolecular illegitimate recombination events.

Authors:  S L Marvo; S R King; S R Jaskunas
Journal:  Proc Natl Acad Sci U S A       Date:  1983-05       Impact factor: 11.205

6.  Rearrangements between the immunoglobulin heavy chain gene JH and C mu regions accompany normal B lymphocyte differentiation in vitro.

Authors:  J L Hurwitz; J J Cebra
Journal:  Nature       Date:  1982-10-21       Impact factor: 49.962

7.  Cytogenetic studies on African Burkitt's lymphoma cell lines: t(8;14), t(2;8) and t(8;22) translocations.

Authors:  A Bernheim; R Berger; G Lenoir
Journal:  Cancer Genet Cytogenet       Date:  1981-06

8.  Clustered illegitimate recombination events in mammalian cells involving very short sequence homologies.

Authors:  H E Ruley; M Fried
Journal:  Nature       Date:  1983 Jul 14-20       Impact factor: 49.962

9.  5' flanking region of immunoglobulin heavy chain constant region genes displays length heterogeneity in germlines of inbred mouse strains.

Authors:  K B Marcu; J Banerji; N A Penncavage; R Lang; N Arnheim
Journal:  Cell       Date:  1980-11       Impact factor: 41.582

10.  Nonrandom chromosome changes involving the Ig gene-carrying chromosomes 12 and 6 in pristane-induced mouse plasmacytomas.

Authors:  S Ohno; M Babonits; F Wiener; J Spira; G Klein; M Potter
Journal:  Cell       Date:  1979-12       Impact factor: 41.582
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  2 in total

1.  Dysfunction of chromosomal loop attachment sites: illegitimate recombination linked to matrix association regions and topoisomerase II.

Authors:  A O Sperry; V C Blasquez; W T Garrard
Journal:  Proc Natl Acad Sci U S A       Date:  1989-07       Impact factor: 11.205

2.  AID-deficient Bcl-xL transgenic mice develop delayed atypical plasma cell tumors with unusual Ig/Myc chromosomal rearrangements.

Authors:  Alexander L Kovalchuk; Wendy duBois; Elizabeth Mushinski; Nicole E McNeil; Carsten Hirt; Chen-Feng Qi; Zhaoyang Li; Siegfried Janz; Tasuku Honjo; Masamichi Muramatsu; Thomas Ried; Timothy Behrens; Michael Potter
Journal:  J Exp Med       Date:  2007-11-06       Impact factor: 14.307
  2 in total

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