Literature DB >> 31238721

Utilization of tumor genomics in clinical practice: an international survey among ASCO members.

Romualdo Barroso-Sousa1,2, Hao Guo3, Piyush Srivastava4, Ted James5, Walter Birch6, Lillian L Siu7, William P Tew8, Sara M Tolaney1.   

Abstract

Aim: To identify patterns of use and barriers to tumor genomic testing among oncologists.
Methods: We surveyed American Society of Clinical Oncology physician members about their use of genomic testing.
Results: Among 11,900 members surveyed, a total of 1000 responded to the survey (participation rate, 8.4%). A total of 75% of the respondents included in the analysis reported ordering tests for at least 1-10% of their patients. Practice setting (academic vs community) was only a determinant in the ordering frequency in North America. Regardless of location, academic oncologists were more likely to prescribe medicine in the context of a clinical trial. Access to clinical trials and costs associated with testing were the barriers identified worldwide.
Conclusion: There is substantial variation in the use of genomic tools according to region and practice setting; yet, the barriers are similar worldwide.

Entities:  

Keywords:  genomics; next-generation sequencing; oncology; precision medicine

Year:  2019        PMID: 31238721     DOI: 10.2217/fon-2019-0010

Source DB:  PubMed          Journal:  Future Oncol        ISSN: 1479-6694            Impact factor:   3.404


  5 in total

Review 1.  Contributions from the 2019 Literature on Bioinformatics and Translational Informatics.

Authors:  Malika Smaïl-Tabbone; Bastien Rance
Journal:  Yearb Med Inform       Date:  2020-08-21

2.  Molecular Tumor Board Review and Improved Overall Survival in Non-Small-Cell Lung Cancer.

Authors:  Bin Huang; Quan Chen; Derek Allison; Riham El Khouli; Keng Hee Peh; James Mobley; Abigail Anderson; Eric B Durbin; Donald Goodin; John L Villano; Rachel W Miller; Susanne M Arnold; Jill M Kolesar
Journal:  JCO Precis Oncol       Date:  2021-09-29

3.  Trends in Use of Next-Generation Sequencing in Patients With Solid Tumors by Race and Ethnicity After Implementation of the Medicare National Coverage Determination.

Authors:  Daniel M Sheinson; William B Wong; Craig S Meyer; Stella Stergiopoulos; Katherine T Lofgren; Carlos Flores; Devon V Adams; Mark E Fleury
Journal:  JAMA Netw Open       Date:  2021-12-01

4.  Community oncologists' perceptions and utilization of large-panel genomic tumor testing.

Authors:  Eric C Anderson; Alexandra C Hinton; Christine W Lary; Anny T H R Fenton; Andrey Antov; Emily Edelman; Petra Helbig; Kate Reed; Susan Miesfeldt; Christian A Thomas; Michael J Hall; J Scott Roberts; Jens Rueter; Paul K J Han
Journal:  BMC Cancer       Date:  2021-11-25       Impact factor: 4.430

5.  Association Between Medicare's National Coverage Determination and Utilization of Next-Generation Sequencing.

Authors:  Daniel M Sheinson; William B Wong; Carlos Flores; Sarika Ogale; Cary P Gross
Journal:  JCO Oncol Pract       Date:  2021-05-27
  5 in total

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