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Literature DB >> 31238472

Clinicopathological and immunohistochemistry correlation in a case of Vogt-Koyanagi-Harada disease.

Dipankar Das¹, Anusha Boddepalli², Jyotirmay Biswas³.

Abstract

Vogt-Koyanagi-Harada (VKH) disease is a systemic disorder causing bilateral panuveitis. Histopathological documentation along with molecular diagnostic evidence in VKH eye is a rarity. We present a 46-year-old woman with VKH with several ocular complications and subsequently enucleation of the right eye was done because of painful blind eye. Patient had clinical complications of VKH and some of the complications were observed in histopathology. Pathology of the case showed nongranulomatous uveitis, indicating the disease in chronic recurrent stage. Immunohistochemistry showed predominant T-cell involvement in this case. The case showed clinicopathological and immunohistochemistry correlation in a case of VKH disease.

Entities: Chemical Disease Gene Species

Keywords: Choroid; Vogt-Koyanagi-Harada disease; choroidal neovascular membrane; immunohistochemistry; panuveitis

Mesh：

Substances：

Year: 2019 PMID： 31238472 PMCID： PMC6611308 DOI： 10.4103/ijo.IJO_1800_18

Source DB: PubMed Journal: Indian J Ophthalmol ISSN： 0301-4738 Impact factor: 1.848

10 in total

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Journal: Int Ophthalmol Date: 2007-03-24 Impact factor: 2.031

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Authors: Narsing A Rao
Journal: Int Ophthalmol Date: 2007-04-14 Impact factor: 2.031

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Journal: Am J Ophthalmol Date: 1983-09 Impact factor: 5.258

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Authors: Kunihiko Yamaki; Shigeaki Ohono
Journal: Ophthalmic Res Date: 2008-04-18 Impact factor: 2.892

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Journal: Ocul Immunol Inflamm Date: 1998-09 Impact factor: 3.070

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Authors: Mayur R Moreker; Sikander A Lodhi; Avinash Pathengay
Journal: Indian J Ophthalmol Date: 2007 Nov-Dec Impact factor: 1.848