Literature DB >> 31237503

Yesterday's Child: How Gene Editing for Enhancement Will Produce Obsolescence-and Why It Matters.

Robert Sparrow1.   

Abstract

Despite the advent of CRISPR, safe and effective gene editing for human enhancement remains well beyond our current technological capabilities. For the discussion about enhancing human beings to be worth having, then, we must assume that gene-editing technology will improve rapidly. However, rapid progress in the development and application of any technology comes at a price: obsolescence. If the genetic enhancements we can provide children get better and better each year, then the enhancements granted to children born in any given year will rapidly go out of date. Sooner or later, every modified child will find him- or herself to be "yesterday's child." The impacts of such obsolescence on our individual, social, and philosophical self-understanding constitute an underexplored set of considerations relevant to the ethics of genome editing.

Entities:  

Keywords:  CRISPR; Ethics; enhancement; gene editing; genome editing; human enhancement; obsolescence

Year:  2019        PMID: 31237503     DOI: 10.1080/15265161.2019.1618943

Source DB:  PubMed          Journal:  Am J Bioeth        ISSN: 1526-5161            Impact factor:   11.229


  7 in total

Review 1.  Responsible Translational Pathways for Germline Gene Editing?

Authors:  Bryan Cwik
Journal:  Curr Stem Cell Rep       Date:  2020-08-21

2.  Could Genetic Enhancement Really Lead to Obsolescence?

Authors:  Peter Zuk; Kristin M Kostick; Gabriel Lázaro-Muñoz
Journal:  Am J Bioeth       Date:  2019-07       Impact factor: 11.229

3.  Revising, Correcting, and Transferring Genes.

Authors:  Bryan Cwik
Journal:  Am J Bioeth       Date:  2020-08       Impact factor: 11.229

4.  Researchers views about perceived harms and benefits of gene editing: A study from the MENA region.

Authors:  Sawsan Abuhammad; Omar F Khabour; Karem H Alzoubi
Journal:  Heliyon       Date:  2021-04-23

5.  Germline genome modification through novel political, ethical, and social lenses.

Authors:  Vicki Xafis; G Owen Schaefer; Markus K Labude; Yujia Zhu; Soren Holm; Roger Sik-Yin Foo; Poh San Lai; Ruth Chadwick
Journal:  PLoS Genet       Date:  2021-09-09       Impact factor: 5.917

6.  Radical enhancement as a moral status de-enhancer.

Authors:  Jesse Gray
Journal:  Monash Bioeth Rev       Date:  2020-12

7.  Enhancing the collectivist critique: accounts of the human enhancement debate.

Authors:  Tess Johnson
Journal:  Med Health Care Philos       Date:  2021-06-16
  7 in total

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