Literature DB >> 31237443

Visualization of Retinal Morphology in rd12 Mice by Scanning Electron Microscopy.

Bertin Mary1, Giridhara R Jayandharan1.   

Abstract

We have evaluated the retinal morphological changes in normal C57BL6/J mice and a retinal degenerative disease (rd12 mice) model using scanning electron microscopy. A method of sample preparation for electron microscopy was developed and the cryosectioned retina was used to study the retinal thickness. Our data demonstrate variation in the neural retina texture between rd12 mice and C57BL6/J mice.

Entities:  

Keywords:  rd12 mice; retina; scanning electron microscopy

Mesh：

Year:  2019        PMID： 31237443      PMCID： PMC7099977          DOI： 10.1089/hum.2019.116

Source DB:  PubMed          Journal:  Hum Gene Ther        ISSN： 1043-0342            Impact factor:   5.695


  5 in total

1.  Novel properties of tyrosine-mutant AAV2 vectors in the mouse retina.

Authors:  Hilda Petrs-Silva; Astra Dinculescu; Qiuhong Li; Wen-Tao Deng; Ji-Jing Pang; Seok-Hong Min; Vince Chiodo; Andy W Neeley; Lakshmanan Govindasamy; Antonette Bennett; Mavis Agbandje-McKenna; Li Zhong; Baozheng Li; Giridhara R Jayandharan; Arun Srivastava; Alfred S Lewin; William W Hauswirth
Journal:  Mol Ther       Date:  2010-11-02       Impact factor: 11.454

2.  Gene therapy for leber congenital amaurosis caused by RPE65 mutations: safety and efficacy in 15 children and adults followed up to 3 years.

Authors:  Samuel G Jacobson; Artur V Cideciyan; Ramakrishna Ratnakaram; Elise Heon; Sharon B Schwartz; Alejandro J Roman; Marc C Peden; Tomas S Aleman; Sanford L Boye; Alexander Sumaroka; Thomas J Conlon; Roberto Calcedo; Ji-Jing Pang; Kirsten E Erger; Melani B Olivares; Cristina L Mullins; Malgorzata Swider; Shalesh Kaushal; William J Feuer; Alessandro Iannaccone; Gerald A Fishman; Edwin M Stone; Barry J Byrne; William W Hauswirth
Journal:  Arch Ophthalmol       Date:  2011-09-12

3.  Identifying photoreceptors in blind eyes caused by RPE65 mutations: Prerequisite for human gene therapy success.

Authors:  Samuel G Jacobson; Tomas S Aleman; Artur V Cideciyan; Alexander Sumaroka; Sharon B Schwartz; Elizabeth A M Windsor; Elias I Traboulsi; Elise Heon; Steven J Pittler; Ann H Milam; Albert M Maguire; Krzysztof Palczewski; Edwin M Stone; Jean Bennett
Journal:  Proc Natl Acad Sci U S A       Date:  2005-04-18       Impact factor: 11.205

4.  Retinal degeneration 12 (rd12): a new, spontaneously arising mouse model for human Leber congenital amaurosis (LCA).

Authors:  Ji-Jing Pang; Bo Chang; Norman L Hawes; Ronald E Hurd; Muriel T Davisson; Jie Li; Syed M Noorwez; Ritu Malhotra; J Hugh McDowell; Shalesh Kaushal; William W Hauswirth; Steven Nusinowitz; Debra A Thompson; John R Heckenlively
Journal:  Mol Vis       Date:  2005-02-28       Impact factor: 2.367

5.  Retinal Thickness Normative Data in Wild-Type Mice Using Customized Miniature SD-OCT.

Authors:  Lee R Ferguson; James M Dominguez; Sankarathi Balaiya; Sandeep Grover; Kakarla V Chalam
Journal:  PLoS One       Date:  2013-06-27       Impact factor: 3.240
  5 in total

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