Qiuju Wang1, Xiaoyu Song1, Yanzhen Zhao2, Qiao He1, Min Shi1, Pingyao Xu1, Sujiao Ni1, Yibo Chen1, Jingying Lin3, Li Zhang1. 1. Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science & Technology of China, Chengdu, PR China. 2. The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, PR China. 3. West China Second University Hospital, Sichuan University, & The Key Laboratory of Birth Defects & Related Diseases of Women & Children (Sichuan University), Ministry of Education, Chengdu, PR China.
Abstract
Aim: To explore whether c-reactive protein/albumin (CRP/Alb) ratio is a poor prognostic factor for patients with oral squamous cell carcinoma (OSCC). Patients & methods: Receiver-operating characteristic analysis was performed to evaluate the optimal cut-off value of CRP/Alb ratio in 240 patients with OSCC. The Kaplan-Meier method was used to plot the overall survival and disease-free survival curves. Cox proportional hazards model was used to implement univariate and multivariate analyses. Results: Preoperative high CRP/Alb ratio was associated with age, advanced stage, lymphatic metastasis, platelet-to-lymphocyte ratio and neutrophil-to-lymphocyte ratio (all p < 0.05). Elevated CRP/Alb ratio independently predicts worse overall survival and disease-free survival of patients with OSCC. Conclusion: Preoperative high CRP/Alb ratio was a poor independent prognostic marker of OSCC.
Aim: To explore whether c-reactive protein/albumin (CRP/Alb) ratio is a poor prognostic factor for patients with oral squamous cell carcinoma (OSCC). Patients & methods: Receiver-operating characteristic analysis was performed to evaluate the optimal cut-off value of CRP/Alb ratio in 240 patients with OSCC. The Kaplan-Meier method was used to plot the overall survival and disease-free survival curves. Cox proportional hazards model was used to implement univariate and multivariate analyses. Results: Preoperative high CRP/Alb ratio was associated with age, advanced stage, lymphatic metastasis, platelet-to-lymphocyte ratio and neutrophil-to-lymphocyte ratio (all p < 0.05). Elevated CRP/Alb ratio independently predicts worse overall survival and disease-free survival of patients with OSCC. Conclusion: Preoperative high CRP/Alb ratio was a poor independent prognostic marker of OSCC.
Authors: Arvi Keinänen; Johanna Uittamo; Magdalena Marinescu-Gava; Satu Kainulainen; Johanna Snäll Journal: BMC Oral Health Date: 2021-03-19 Impact factor: 2.757
Authors: Mahlatse C M Kgokolo; Katherine Anderson; Shalate C Siwele; Helen C Steel; Luyanda L I Kwofie; Mike M Sathekge; Pieter W A Meyer; Bernardo L Rapoport; Ronald Anderson Journal: Front Oncol Date: 2022-02-11 Impact factor: 6.244