Sex estimation using paranasal sinus discriminant analysis: a new approach via cone beam computerized tomography volume analysis.

Sex estimation is an important step for subject identification in forensic medicine, to which paranasal sinuses may contribute, as they remain intact even upon severe damage to the skull and other bones. Cone beam computerized tomography (CBCT) is an excellent tool in the examination of these structures. The present study aimed to evaluate the maxillary, frontal and sphenoidal sinuses through a discriminant analysis to determine the sex correlations with foramen magnum measurements were also assessed. Two-hundred cranial CBCT scans were analysed. The volume of the maxillary, frontal and sphenoidal sinuses were measured using the ITK-SNAP software (4.0.2). Student's t test and the Mann-Whitney test were applied for the descriptive analysis of independent samples, and data were subjected to discriminant analysis. The volumes of the maxillary, frontal and sphenoidal sinuses of female subjects were smaller than those of male subjects (p < 0.001). Upon summing up the volumes of the evaluated paranasal sinuses, the chances to correctly determine an individual's gender are 96.2% and 92.7% for males and females, respectively. When correlating said values with foramen magnum measurements, sex identification chances increase to 100%. Thus, adult paranasal sinus volumes analysed by CBCT may be useful for sex identification when summed together and correlated with foramen magnum measurements.