Literature DB >> 31236625

The assembly of succinate dehydrogenase: a key enzyme in bioenergetics.

Behrooz Moosavi1, Edward A Berry2, Xiao-Lei Zhu1, Wen-Chao Yang1, Guang-Fu Yang3.   

Abstract

Succinate dehydrogenase (SDH) also known as complex II or succinate:quinone oxidoreductase is an enzyme involved in both oxidative phosphorylation and tricarboxylic acid cycle; the processes that generate energy. SDH is a multi-subunit enzyme which requires a series of proteins for its proper assembly at several steps. This enzyme has medical significance as there is a broad range of human diseases from cancers to neurodegeneration related to SDH malfunction. Some of these disorders have recently been linked to defective assembly factors, reinvigorating further research in this area. Apart from that this enzyme has agricultural importance as many fungicides have been/will be designed targeting specifically this enzyme in plant fungal pathogens. In addition, we speculate it might be possible to design novel fungicides specifically targeting fungal assembly factors. Considering the medical and agricultural implications of SDH, the aim of this review is an overview of the SDH assembly factors and critical analysis of controversial issues around them.

Entities:  

Keywords:  Complex II; Fumarate reductase; Mitochondria; Oxidative phosphorylation; Succinate:quinone oxidoreductases; Tricarboxylic acid cycle

Mesh：

Substances：

Year:  2019        PMID： 31236625     DOI： 10.1007/s00018-019-03200-7

Source DB:  PubMed          Journal:  Cell Mol Life Sci        ISSN： 1420-682X            Impact factor:   9.261


  123 in total

1.  The high potential iron-sulfur center in Escherichia coli fumarate reductase is a three-iron cluster.

Authors:  J E Morningstar; M K Johnson; G Cecchini; B A Ackrell; E B Kearney
Journal:  J Biol Chem       Date:  1985-11-05       Impact factor: 5.157

2.  SDHAF4 promotes mitochondrial succinate dehydrogenase activity and prevents neurodegeneration.

Authors:  Jonathan G Van Vranken; Daniel K Bricker; Noah Dephoure; Steven P Gygi; James E Cox; Carl S Thummel; Jared Rutter
Journal:  Cell Metab       Date:  2014-06-19       Impact factor: 27.287

3.  A requirement for matrix processing peptidase but not for mitochondrial chaperonin in the covalent attachment of FAD to the yeast succinate dehydrogenase flavoprotein.

Authors:  K M Robinson; B D Lemire
Journal:  J Biol Chem       Date:  1996-02-23       Impact factor: 5.157

4.  Subunit 8 of the Saccharomyces cerevisiae cytochrome bc1 complex interacts with succinate-ubiquinone reductase complex.

Authors:  C Bruel; R Brasseur; B L Trumpower
Journal:  J Bioenerg Biomembr       Date:  1996-02       Impact factor: 2.945

5.  Cloning by functional complementation, and inactivation, of the Schizosaccharomyces pombe homologue of the Saccharomyces cerevisiae gene ABC1.

Authors:  N Bonnefoy; M Kermorgant; P Brivet-Chevillotte; G Dujardin
Journal:  Mol Gen Genet       Date:  1996-05-23

6.  Escherichia coli succinate dehydrogenase variant lacking the heme b.

Authors:  Quang M Tran; Richard A Rothery; Elena Maklashina; Gary Cecchini; Joel H Weiner
Journal:  Proc Natl Acad Sci U S A       Date:  2007-11-07       Impact factor: 11.205

Review 7.  Defining a direction: electron transfer and catalysis in Escherichia coli complex II enzymes.

Authors:  Elena Maklashina; Gary Cecchini; Sergei A Dikanov
Journal:  Biochim Biophys Acta       Date:  2013-02-08

Review 8.  What's in a covalent bond? On the role and formation of covalently bound flavin cofactors.

Authors:  Dominic P H M Heuts; Nigel S Scrutton; William S McIntire; Marco W Fraaije
Journal:  FEBS J       Date:  2009-05-05       Impact factor: 5.542

9.  Suppressors of superoxide dismutase (SOD1) deficiency in Saccharomyces cerevisiae. Identification of proteins predicted to mediate iron-sulfur cluster assembly.

Authors:  J Strain; C R Lorenz; J Bode; S Garland; G A Smolen; D T Ta; L E Vickery; V C Culotta
Journal:  J Biol Chem       Date:  1998-11-20       Impact factor: 5.157

10.  FLX1 codes for a carrier protein involved in maintaining a proper balance of flavin nucleotides in yeast mitochondria.

Authors:  A Tzagoloff; J Jang; D M Glerum; M Wu
Journal:  J Biol Chem       Date:  1996-03-29       Impact factor: 5.157
View more
  13 in total

1.  The roles of SDHAF2 and dicarboxylate in covalent flavinylation of SDHA, the human complex II flavoprotein.

Authors:  Pankaj Sharma; Elena Maklashina; Gary Cecchini; T M Iverson
Journal:  Proc Natl Acad Sci U S A       Date:  2020-09-04       Impact factor: 11.205

Review 2.  The assembly, regulation and function of the mitochondrial respiratory chain.

Authors:  Irene Vercellino; Leonid A Sazanov
Journal:  Nat Rev Mol Cell Biol       Date:  2021-10-07       Impact factor: 94.444

Review 3.  Cushing syndrome: Old and new genes.

Authors:  Christina Tatsi; Chelsi Flippo; Constantine A Stratakis
Journal:  Best Pract Res Clin Endocrinol Metab       Date:  2020-04-02       Impact factor: 4.690

4.  Iron Deficiency and Recovery in Yeast: A Quantitative Proteomics Approach.

Authors:  Jose Navarrete-Perea; Angel Guerra-Moreno; Jonathan Van Vranken; Marta Isasa; Joao A Paulo; Steven P Gygi
Journal:  J Proteome Res       Date:  2021-04-02       Impact factor: 4.466

5.  CAMKK2 regulates mitochondrial function by controlling succinate dehydrogenase expression, post-translational modification, megacomplex assembly, and activity in a cell-type-specific manner.

Authors:  Mohammad Golam Sabbir; Carla G Taylor; Peter Zahradka
Journal:  Cell Commun Signal       Date:  2021-09-25       Impact factor: 5.712

6.  Western Diet Decreases the Liver Mitochondrial Oxidative Flux of Succinate: Insight from a Murine NAFLD Model.

Authors:  Pavla Staňková; Otto Kučera; Eva Peterová; Moustafa Elkalaf; David Rychtrmoc; Jan Melek; Miroslav Podhola; Veronika Zubáňová; Zuzana Červinková
Journal:  Int J Mol Sci       Date:  2021-06-27       Impact factor: 5.923

7.  Crystallographic investigation of the ubiquinone binding site of respiratory Complex II and its inhibitors.

Authors:  Li-Shar Huang; Peter Lümmen; Edward A Berry
Journal:  Biochim Biophys Acta Proteins Proteom       Date:  2021-06-03       Impact factor: 4.125

Review 8.  The Genetics of Pituitary Adenomas.

Authors:  Christina Tatsi; Constantine A Stratakis
Journal:  J Clin Med       Date:  2019-12-21       Impact factor: 4.241

Review 9.  Mitochondrial OXPHOS Biogenesis: Co-Regulation of Protein Synthesis, Import, and Assembly Pathways.

Authors:  Jia Xin Tang; Kyle Thompson; Robert W Taylor; Monika Oláhová
Journal:  Int J Mol Sci       Date:  2020-05-28       Impact factor: 5.923

10.  Succinate Dehydrogenase-Regulated Phosphoenolpyruvate Carboxykinase Sustains Copulation Fitness in Aging C. elegans Males.

Authors:  Jimmy Goncalves; Yufeng Wan; Xiaoyan Guo; Kyoungsun Rha; Brigitte LeBoeuf; Liusuo Zhang; Kerolayne Estler; L René Garcia
Journal:  iScience       Date:  2020-03-19
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.