Literature DB >> 31233010

Retracted: Expression of Lymphocyte-Activation Gene 3 (LAG-3) Immune Checkpoint Receptor Identifies a Tumor-Reactive T Cell Population in the Peripheral Blood of Patients with Colorectal Cancer.

Lefu Huang1, Guoliang Qiao2, Jingping Wu1, Jun Ren1.   

Abstract

This article is retracted due to authors' claims in regards to errors in data and statistical analyses. Authors' message: We greatly regret to inform you that we just discovered some fatal errors in the statistical analysis, in which we mistakenly used the cultured cells TCR sequencing data as the results of CD8+ LAG3+ and CD8 LAG3-T cells. Therefore, the current results and data have serious defects and do not accurately represent the sorted cells. On behalf of all the contributing authors of the manuscript, we have decided to immediately retract the manuscript titled "LAG-3 receptor identifies a higher tumor-reactive cell population in the peripheral blood of colorectal cancer patients" to avoid further problems.

Entities:  

Year:  2019        PMID: 31233010      PMCID: PMC6588518          DOI: 10.12659/MSM.917907

Source DB:  PubMed          Journal:  Med Sci Monit        ISSN: 1234-1010


Retraction Notice: This article is retracted due to authors’ claims in regards to errors in data and statistical analyses. Authors’ message: We greatly regret to inform you that we just discovered some fatal errors in the statistical analysis, in which we mistakenly used the cultured cells TCR sequencing data as the results of CD8+ LAG3+ and CD8 LAG3-T cells. Therefore, the current results and data have serious defects and do not accurately represent the sorted cells. On behalf of all the contributing authors of the manuscript, we have decided to immediately retract the manuscript titled “LAG-3 receptor identifies a higher tumor-reactive cell population in the peripheral blood of colorectal cancer patients” to avoid further problems.
  1 in total

1.  Expression of Lymphocyte-Activation Gene 3 (LAG-3) Immune Checkpoint Receptor Identifies a Tumor-Reactive T Cell Population in the Peripheral Blood of Patients with Colorectal Cancer.

Authors:  Lefu Huang; Guoliang Qiao; Jingping Wu; Jun Ren
Journal:  Med Sci Monit       Date:  2019-05-11
  1 in total
  1 in total

Review 1.  The landscape of immune checkpoints expression in non-small cell lung cancer: a narrative review.

Authors:  Yu Liu; Peixin Chen; Hao Wang; Shengyu Wu; Sha Zhao; Yayi He; Caicun Zhou; Fred R Hirsch
Journal:  Transl Lung Cancer Res       Date:  2021-02
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.