Michihiro Kon1,2, Yoshiko Ebi2, Kohei Nakagaki2,3. 1. School of International Liberal Studies, Chukyo University, Nagoya, Japan. 2. Department of Sports Sciences, Japan Institute of Sports Sciences, Tokyo, Japan. 3. Department of Sports Sciences, Yamanashi Gakuin University, Kofu, Yamanashi, Japan.
Abstract
CONTEXT: Insulin resistance is the main triggering factor for type 2 diabetes. Recently, it has been reported that high-intensity sprint interval training (SIT) was effective for improving glucose metabolism and insulin sensitivity despite lower training volume. However, the mechanisms underlying the SIT-induced increases in glucose metabolism and insulin sensitivity have not been well-understood. Follistatin-like 1 (FSTL1) and apelin, which are novel myokines, have a favourable effect on glucose metabolism. OBJECTIVE: We examined the impact of acute SIT on FSTL1 and apelin secretions. METHODS: Eight healthy men were enrolled in this study. The subjects performed acute SIT consisting of four 30-s all-out cycling efforts with 4-min rest periods. Blood samples were obtained before and after the acute SIT to measure FSTL1 and apelin concentrations. RESULTS: FSTL1 and apelin both significantly increased following acute SIT. CONCLUSION: Acute SIT may be an effective stimulus for increasing of FSTL1 and apelin secretions.
CONTEXT: Insulin resistance is the main triggering factor for type 2 diabetes. Recently, it has been reported that high-intensity sprint interval training (SIT) was effective for improving glucose metabolism and insulin sensitivity despite lower training volume. However, the mechanisms underlying the SIT-induced increases in glucose metabolism and insulin sensitivity have not been well-understood. Follistatin-like 1 (FSTL1) and apelin, which are novel myokines, have a favourable effect on glucose metabolism. OBJECTIVE: We examined the impact of acute SIT on FSTL1 and apelin secretions. METHODS: Eight healthy men were enrolled in this study. The subjects performed acute SIT consisting of four 30-s all-out cycling efforts with 4-min rest periods. Blood samples were obtained before and after the acute SIT to measure FSTL1 and apelin concentrations. RESULTS: FSTL1 and apelin both significantly increased following acute SIT. CONCLUSION: Acute SIT may be an effective stimulus for increasing of FSTL1 and apelin secretions.
Authors: Kinga Humińska-Lisowska; Jan Mieszkowski; Andrzej Kochanowicz; Aleksandra Bojarczuk; Bartłomiej Niespodziński; Paulina Brzezińska; Błażej Stankiewicz; Monika Michałowska-Sawczyn; Anna Grzywacz; Miroslav Petr; Paweł Cięszczyk Journal: Int J Environ Res Public Health Date: 2022-07-19 Impact factor: 4.614