| Literature DB >> 31232100 |
Yu-Kun Lin1,2, Chun-Lan Xie2, Cui-Ping Xing2, Bao-Qu Wang2, Xiao-Xue Tian2, Jin-Mei Xia2, Ling-Yun Jia1, Ying-Ni Pan1, Xian-Wen Yang2.
Abstract
From the deep-sea-derived fungus Aspergillus candidus, one novel (1) and three known (2-4) p-terphenyl derivates were isolated. The structure of the new compound was established mainly on the basis of extensive analysis of 1D and 2D NMR data. All four isolates were tested for in vitro anti-food allergic and antitumor bioactivities. Compounds 3 and 4 showed potent antiproliferative effect against four cancer cells of Hela, Eca-109, Bel-7402, and PANC-1 with IC50 values ranging from 5.5 μM to 9.4 μM.Entities:
Keywords: Fungus; anti-allergy; antitumor; in vitro; the Atlantic Ocean
Mesh：
Substances：
Year: 2019 PMID： 31232100 DOI： 10.1080/14786419.2019.1633651
Source DB: PubMed Journal: Nat Prod Res ISSN： 1478-6419 Impact factor: 2.861