Literature DB >> 31229899

Generation of two induced pluripotent stem cell lines (MUSIi011-A and MUSIi011-B) from peripheral blood T lymphocytes of a healthy individual.

Ratchapong Netsrithong1, Nutchanawan Promnakhon1, Bootsakorn Boonkaew2, Chinnavuth Vatanashevanopakorn3, Kovit Pattanapanyasat4, Methichit Wattanapanitch5.   

Abstract

Activated T lymphocytes of a healthy individual were reprogrammed to induced pluripotent stem cells (iPSCs) using Sendai viral vectors. Two iPSC lines, MUSIi011-A and MUSIi011-B, were established and characterized for the expression of pluripotent markers. Both iPSC lines were able to differentiate into cells of three embryonic germ layers via embryoid body formation, exhibited normal karyotypes and were free of viral genome and transgenes at passage 15. These T lymphocyte-derived iPSCs (T-iPSCs) represent a useful starting cell source for developing next-generation immune cells such as chimeric antigen receptor (CAR)-engineered iPSC-derived T lymphocytes for the application in adoptive immunotherapy.
Copyright © 2019 The Authors. Published by Elsevier B.V. All rights reserved.

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Year:  2019        PMID： 31229899     DOI： 10.1016/j.scr.2019.101487

Source DB:  PubMed          Journal:  Stem Cell Res        ISSN： 1873-5061            Impact factor:   2.020


  3 in total

1.  Episomal reprogramming of Duchenne muscular dystrophy patients derived CD3+ T cells towards induced pluripotent stem cells.

Authors:  Mehwish Zehravi; Mohsin Wahid; Junaid Ashraf
Journal:  Pak J Med Sci       Date:  2021 Mar-Apr       Impact factor: 1.088

Review 2.  Induced Pluripotent Stem Cells (iPSCs) Provide a Potentially Unlimited T Cell Source for CAR-T Cell Development and Off-the-Shelf Products.

Authors:  Muhammad Sadeqi Nezhad; Meghdad Abdollahpour-Alitappeh; Behzad Rezaei; Mahboubeh Yazdanifar; Alexander Marcus Seifalian
Journal:  Pharm Res       Date:  2021-06-10       Impact factor: 4.200

3.  Multilineage differentiation potential of hematoendothelial progenitors derived from human induced pluripotent stem cells.

Authors:  Ratchapong Netsrithong; Siriwal Suwanpitak; Bootsakorn Boonkaew; Kongtana Trakarnsanga; Lung-Ji Chang; Chartsiam Tipgomut; Chinnavuth Vatanashevanopakorn; Kovit Pattanapanyasat; Methichit Wattanapanitch
Journal:  Stem Cell Res Ther       Date:  2020-11-11       Impact factor: 6.832
  3 in total

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