Literature DB >> 31228925

Prolactin Receptor Isoforms as the Basis of Tissue-Specific Action of Prolactin in the Norm and Pathology.

P A Abramicheva1, O V Smirnova2.   

Abstract

The review describes functional and structural features of different isoforms of prolactin receptor, mechanisms of signaling pathway activation, and molecular messengers involved in the transmission and termination of signal from the prolactin receptor isoforms. Changes in the ratio between prolactin receptor isoforms, key mediators of prolactin signal transduction and termination in various organs and tissues, are analyzed. Special attention is given to the role of molecular mediators and the ratio between the isoforms in normal physiological functions and pathologies. Approaches for therapeutic correction of prolactin signaling impairments are discussed.

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Year:  2019        PMID: 31228925     DOI: 10.1134/S0006297919040011

Source DB:  PubMed          Journal:  Biochemistry (Mosc)        ISSN: 0006-2979            Impact factor:   2.487


  5 in total

1.  Differential modulation of natural killer cell cytotoxicity by 17β-estradiol and prolactin through the NKG2D/NKG2DL axis in cervical cancer cells.

Authors:  Alejandro Godoy-Pacheco; Mariel García-Chagollán; Adrián Ramírez-De-Arellano; Christian David Hernández-Silva; Julio César Villegas-Pineda; Inocencia Guadalupe Ramírez-López; José Sergio Zepeda-Nuño; Adriana Aguilar-Lemarroy; Ana Laura Pereira-Suárez
Journal:  Oncol Lett       Date:  2022-06-28       Impact factor: 3.111

2.  Expression of long-form prolactin receptor is associated with lower disease-free and overall survival in node-negative breast cancer patients.

Authors:  Doonyapat Sa-Nguanraksa; Kwanlada Mitpakdi; Norasate Samarnthai; Thanawat Thumrongtaradol; Pornchai O-Charoenrat
Journal:  Gland Surg       Date:  2021-01

3.  Prolactin Rescues Immature B Cells from Apoptosis-Induced BCR-Aggregation through STAT3, Bcl2a1a, Bcl2l2, and Birc5 in Lupus-Prone MRL/lpr Mice.

Authors:  Rocio Flores-Fernández; Angélica Aponte-López; Mayra C Suárez-Arriaga; Patricia Gorocica-Rosete; Alberto Pizaña-Venegas; Luis Chávez-Sanchéz; Francico Blanco-Favela; Ezequiel M Fuentes-Pananá; Adriana K Chávez-Rueda
Journal:  Cells       Date:  2021-02-04       Impact factor: 6.600

Review 4.  The crucial role of prolactin-lactogenic hormone in Covid-19.

Authors:  Hayder M Al-Kuraishy; Ali I Al-Gareeb; Monica Butnariu; Gaber El-Saber Batiha
Journal:  Mol Cell Biochem       Date:  2022-02-11       Impact factor: 3.842

Review 5.  Pharmacological Benefits and Risk of Using Hormones in Organ Perfusion and Preservation Solutions in the Aspect of Minimizing Hepatic Ischemia-Reperfusion Injury during Storage.

Authors:  Aneta Ostróżka-Cieślik; Barbara Dolińska
Journal:  Biomed Res Int       Date:  2019-11-11       Impact factor: 3.411

  5 in total

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