Literature DB >> 31228150

The Rat: A Model Used in Biomedical Research.

Jennifer R Smith1, Elizabeth R Bolton2, Melinda R Dwinell3,4.   

Abstract

The laboratory rat, Rattus norvegicus, has been used in biomedical research for more than 150 years, and in many cases remains the model of choice for studies of physiology, behavior, and complex human disease. This book provides detailed information on a number of methodologies that can be used in rat. This chapter gives an introduction to rat as a species and as a biomedical model, providing historical information, a brief introduction to the current state of rat research, and a perspective on the future of rat as a model for human disease.

Entities:  

Keywords:  Biomedical research; Data; History; Models; Rat; Resources

Mesh：

Year:  2019        PMID： 31228150     DOI： 10.1007/978-1-4939-9581-3_1

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  6 in total

Review 1.  Understanding and Treating Niemann-Pick Type C Disease: Models Matter.

Authors:  Valentina Pallottini; Frank W Pfrieger
Journal:  Int J Mol Sci       Date:  2020-11-26       Impact factor: 5.923

Review 2.  Relevance of Peptide Homeostasis in Metabolic Retinal Degenerative Disorders: Curative Potential in Genetically Modified Mice.

Authors:  Etelka Pöstyéni; Alma Ganczer; Andrea Kovács-Valasek; Robert Gabriel
Journal:  Front Pharmacol       Date:  2022-01-13       Impact factor: 5.810

3.  The Rat Genome Database (RGD) facilitates genomic and phenotypic data integration across multiple species for biomedical research.

Authors:  M L Kaldunski; J R Smith; G T Hayman; K Brodie; J L De Pons; W M Demos; A C Gibson; M L Hill; M J Hoffman; L Lamers; S J F Laulederkind; H S Nalabolu; K Thorat; J Thota; M Tutaj; M A Tutaj; M Vedi; S J Wang; S Zacher; M R Dwinell; A E Kwitek
Journal:  Mamm Genome       Date:  2021-11-05       Impact factor: 2.957

4.  Creation of X-linked Alport syndrome rat model with Col4a5 deficiency.

Authors:  Tomoe Kobayashi; Mayumi Kohno; Masumi Namba; Takayuki Koyano; Takuo Hirose; Masaki Fukushima; Makoto Matsuyama
Journal:  Sci Rep       Date:  2021-10-21       Impact factor: 4.996

Review 5.  The Alliance of Genome Resources: Building a Modern Data Ecosystem for Model Organism Databases.

Authors: 
Journal:  Genetics       Date:  2019-12       Impact factor: 4.562

Review 6.  Genome-to-phenome research in rats: progress and perspectives.

Authors:  Amy L Zinski; Shane Carrion; Jennifer J Michal; Maria A Gartstein; Raymond M Quock; Jon F Davis; Zhihua Jiang
Journal:  Int J Biol Sci       Date:  2021-01-01       Impact factor: 6.580
  6 in total

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