| Literature DB >> 3122790 |
P Van de Perre1, D Jacobs, S Sprecher-Goldberger.
Abstract
Using a mechanical model, we studied human immunodeficiency virus (HIV) leakage through six different trademark condoms. The presence of the recovered virus was determined after passage to MT-2 cells and to cultured mitogen-stimulated normal human peripheral blood mononuclear cells (PMC). Only the natural membrane condom showed virus leakage after inside pressure. In addition, the kinetics of virus inactivation at 37 degrees C were followed inside and outside the condom. The virus was partially inactivated after 10 min at 37 degrees C inside the condom, but the degree of inactivation seemed higher in some of the trademark condoms.Entities:
Keywords: Acquired Immunodeficiency Syndrome; Africa; Africa South Of The Sahara; Americas; Barrier Methods; Condom; Contraception; Contraceptive Agents; Contraceptive Methods; Developed Countries; Developing Countries; Diseases; Enzymes; Europe; Family Planning; Hiv Infections; Homosexuals; In Vitro; Infections; Ingredients And Chemicals; Middle Africa; North America; Northern America; Polymers; Population At Risk; Reproductive Tract Infections; Sex Behavior; Sexually Transmitted Diseases; Spermicidal Contraceptive Agents; United States; Viral Diseases
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Year: 1987 PMID： 3122790
Source DB: PubMed Journal: AIDS ISSN： 0269-9370 Impact factor: 4.177