Henrik Johansson1, Katarina Norlander2, Andrei Malinovschi3. 1. Department of Medical Sciences, Clinical Physiology, Uppsala University, Box 256, SE-751 05, Uppsala, Sweden; Department of Medical Sciences, Respiratory-, Allergy- and Sleep Research, Uppsala University, Box 256, SE-751 05, Uppsala, Sweden; Department of Neuroscience, Physiotherapy, Uppsala University, Box 256, SE-751 05, Uppsala, Sweden. Electronic address: henrik.johansson@neuro.uu.se. 2. Department of Surgical Sciences, Otorhinolaryngology and Head and Neck Surgery, Uppsala University, Box 256, SE-751 05, Uppsala, Sweden. 3. Department of Medical Sciences, Clinical Physiology, Uppsala University, Box 256, SE-751 05, Uppsala, Sweden.
Abstract
BACKGROUND: Exercise-induced airway symptoms are common in adolescents. Little is known about the development of symptoms from adolescence to early adulthood. Therefore, we studied the prevalence, incidence, and remission of exercise-induced airway symptoms (including wheeze, cough, chest and throat tightness, hoarseness, and stridor) in adolescents, over a five-year period. METHODS: In 2011, all adolescents aged 12-13 years in Uppsala (n = 3 838) were invited to answer a questionnaire on exercise-induced airway symptoms. All responding adolescents (n = 2 309) were invited to answer the same questionnaire again after five years. In total, 1 002 adolescents responded (43.4%). RESULTS: The prevalence of exercise-induced airway symptoms increased from 25% at baseline to 49% at follow-up (p < 0.001). More females than males reported symptoms at both time points. The incidence of airway symptoms was 42.2%, with no sex differences. More males than females reported symptom remission (20.2 vs. 10.7%, p < 0.001). Females reported a higher asthma prevalence at follow-up than at baseline (7.6 vs. 15.2%), while males did not (10.9 vs. 8.0%), leading to a sex difference in prevalence at follow-up (p < 0.001). Smoking and baseline respiratory symptoms were associated with an increased risk of reporting symptoms at follow-up. CONCLUSIONS: A twofold increase in the prevalence of exercise-induced airway symptoms over a five-year period was found in this cohort. Females were more likely to report symptoms at both time points. Knowledge of these age-related changes in symptoms and their association to female gender is useful for future studies and healthcare providers.
BACKGROUND: Exercise-induced airway symptoms are common in adolescents. Little is known about the development of symptoms from adolescence to early adulthood. Therefore, we studied the prevalence, incidence, and remission of exercise-induced airway symptoms (including wheeze, cough, chest and throat tightness, hoarseness, and stridor) in adolescents, over a five-year period. METHODS: In 2011, all adolescents aged 12-13 years in Uppsala (n = 3 838) were invited to answer a questionnaire on exercise-induced airway symptoms. All responding adolescents (n = 2 309) were invited to answer the same questionnaire again after five years. In total, 1 002 adolescents responded (43.4%). RESULTS: The prevalence of exercise-induced airway symptoms increased from 25% at baseline to 49% at follow-up (p < 0.001). More females than males reported symptoms at both time points. The incidence of airway symptoms was 42.2%, with no sex differences. More males than females reported symptom remission (20.2 vs. 10.7%, p < 0.001). Females reported a higher asthma prevalence at follow-up than at baseline (7.6 vs. 15.2%), while males did not (10.9 vs. 8.0%), leading to a sex difference in prevalence at follow-up (p < 0.001). Smoking and baseline respiratory symptoms were associated with an increased risk of reporting symptoms at follow-up. CONCLUSIONS: A twofold increase in the prevalence of exercise-induced airway symptoms over a five-year period was found in this cohort. Females were more likely to report symptoms at both time points. Knowledge of these age-related changes in symptoms and their association to female gender is useful for future studies and healthcare providers.
Authors: Rita C Faleiro; Eliane V Mancuzo; Fernanda C Lanza; Mônica V N P Queiroz; Luciano F L de Oliveira; Vinicius O Ganem; Laura B Lasmar Journal: Front Physiol Date: 2021-01-26 Impact factor: 4.566
Authors: Astrid Sandnes; Tiina Andersen; Hege Havstad Clemm; Magnus Hilland; John-Helge Heimdal; Thomas Halvorsen; Ola Drange Røksund; Maria Vollsæter Journal: Eur Arch Otorhinolaryngol Date: 2021-12-26 Impact factor: 3.236