| Literature DB >> 31226287 |
Parvarish Sharma1, Meenu Mehta1, Daljeet Singh Dhanjal2, Simran Kaur2, Gaurav Gupta3, Harjeet Singh4, Lakshmi Thangavelu5, S Rajeshkumar5, Murtaza Tambuwala6, Hamid A Bakshi6, Dinesh Kumar Chellappan7, Kamal Dua8, Saurabh Satija9.
Abstract
Cancer is one of the major diseases that cause a high number of deaths globally. Of the major types of cancers, lung cancer is known to be the most chronic form of cancer in the world. The conventional management of lung cancer includes different medical interventions like chemotherapy, surgical removal, and radiation therapy. However, this type of approach lacks specificity and also harms the adjacent normal cells. Lately, nanotechnology has emerged as a promising intervention in the management and treatment of lung cancers. Nanotechnology has revolutionized the existing modalities and focuses primarily on reducing toxicity and improving the bioavailability of anticancer drugs to the target tumor cells. Nanocarrier systems are being currently used extensively to exploit and to overcome the obstructions induced by cancers in the lungs. The nano-carrier-loaded therapeutic drug delivery methods have shown promising potential in treating lung cancer as its target is to control the growth of tumor cells. In this review, various modes of nano drug delivery options like liposomes, dendrimers, quantum dots, carbon nanotubes and metallic nanoparticles have been discussed. Nano-carrier drug delivery systems emerge as a promising approach and thus is expected to provide newer and advanced avenues in cancer therapeutics.Entities:
Keywords: Cancer; Lung cancer; Nano-carrier; Nanotechnology; Target drug delivery
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Year: 2019 PMID: 31226287 DOI: 10.1016/j.cbi.2019.06.033
Source DB: PubMed Journal: Chem Biol Interact ISSN: 0009-2797 Impact factor: 5.192