Literature DB >> 31225432

TFEB-mTORC1 feedback loop in metabolism and cancer.

Chiara Di Malta1, Andrea Ballabio1,2,3,4.   

Abstract

Entities:  

Keywords:  RAGD; TFEB; cancer; mTORC1; metabolism; transcription

Year:  2017        PMID： 31225432      PMCID： PMC6551658          DOI： 10.15698/cst2017.10.103

Source DB:  PubMed          Journal:  Cell Stress        ISSN： 2523-0204


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  20 in total

1.  Mitf and Tfe3, two members of the Mitf-Tfe family of bHLH-Zip transcription factors, have important but functionally redundant roles in osteoclast development.

Authors:  Eiríkur Steingrimsson; Lino Tessarollo; Bhavani Pathak; Ling Hou; Heinz Arnheiter; Neal G Copeland; Nancy A Jenkins
Journal:  Proc Natl Acad Sci U S A       Date:  2002-04-02       Impact factor: 11.205

2.  The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1.

Authors:  Yasemin Sancak; Timothy R Peterson; Yoav D Shaul; Robert A Lindquist; Carson C Thoreen; Liron Bar-Peled; David M Sabatini
Journal:  Science       Date:  2008-05-22       Impact factor: 47.728

3.  Biology and clinical relevance of the micropthalmia family of transcription factors in human cancer.

Authors:  Rizwan Haq; David E Fisher
Journal:  J Clin Oncol       Date:  2011-06-13       Impact factor: 44.544

4.  Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids.

Authors:  Yasemin Sancak; Liron Bar-Peled; Roberto Zoncu; Andrew L Markhard; Shigeyuki Nada; David M Sabatini
Journal:  Cell       Date:  2010-04-08       Impact factor: 41.582

Review 5.  Autophagy and metabolism.

Authors:  Joshua D Rabinowitz; Eileen White
Journal:  Science       Date:  2010-12-03       Impact factor: 47.728

6.  Novel G proteins, Rag C and Rag D, interact with GTP-binding proteins, Rag A and Rag B.

Authors:  T Sekiguchi; E Hirose; N Nakashima; M Ii; T Nishimoto
Journal:  J Biol Chem       Date:  2000-11-09       Impact factor: 5.157

7.  A gene network regulating lysosomal biogenesis and function.

Authors:  Marco Sardiello; Michela Palmieri; Alberto di Ronza; Diego Luis Medina; Marta Valenza; Vincenzo Alessandro Gennarino; Chiara Di Malta; Francesca Donaudy; Valerio Embrione; Roman S Polishchuk; Sandro Banfi; Giancarlo Parenti; Elena Cattaneo; Andrea Ballabio
Journal:  Science       Date:  2009-06-25       Impact factor: 47.728

8.  TFEB links autophagy to lysosomal biogenesis.

Authors:  Carmine Settembre; Chiara Di Malta; Vinicia Assunta Polito; Moises Garcia Arencibia; Francesco Vetrini; Serkan Erdin; Serpil Uckac Erdin; Tuong Huynh; Diego Medina; Pasqualina Colella; Marco Sardiello; David C Rubinsztein; Andrea Ballabio
Journal:  Science       Date:  2011-05-26       Impact factor: 47.728

9.  A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB.

Authors:  Carmine Settembre; Roberto Zoncu; Diego L Medina; Francesco Vetrini; Serkan Erdin; SerpilUckac Erdin; Tuong Huynh; Mathieu Ferron; Gerard Karsenty; Michel C Vellard; Valeria Facchinetti; David M Sabatini; Andrea Ballabio
Journal:  EMBO J       Date:  2012-02-17       Impact factor: 11.598

10.  Regulation of TORC1 by Rag GTPases in nutrient response.

Authors:  Eunjung Kim; Pankuri Goraksha-Hicks; Li Li; Thomas P Neufeld; Kun-Liang Guan
Journal:  Nat Cell Biol       Date:  2008-07-06       Impact factor: 28.824
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  2 in total

1.  Isobacachalcone induces autophagy and improves the outcome of immunogenic chemotherapy.

Authors:  Qi Wu; Ai-Ling Tian; Sylvère Durand; Fanny Aprahamian; Nitharsshini Nirmalathasan; Wei Xie; Peng Liu; Liwei Zhao; Shuai Zhang; Hui Pan; Didac Carmona-Gutierrez; Frank Madeo; Yi Tu; Oliver Kepp; Guido Kroemer
Journal:  Cell Death Dis       Date:  2020-11-26       Impact factor: 8.469

Review 2.  How Lysosomes Sense, Integrate, and Cope with Stress.

Authors:  Paul Saftig; Rosa Puertollano
Journal:  Trends Biochem Sci       Date:  2020-10-01       Impact factor: 13.807
  2 in total

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