Corpus callosotomy for epilepsy. I. Seizure effects.

Twenty-two patients were analyzed 2 or more years after corpus callosum section (9 partial, 13 total). Forty-one percent had class 1 outcome (elimination of secondarily generalized and complex partial seizures), 32% had class 2 outcome (elimination of secondarily generalized seizures), and 27% had class 3 outcome (no appreciable change). Total section was twice as effective in abolishing secondarily generalized seizures as was partial section (77% versus 35%). Statistically significant associations were seen between focal CT lesions and class 1 outcome, and between IQ less than 45 and class 2 or 3 outcome.