Literature DB >> 31216458

CXCR3-CXCL9: It's All in the Tumor.

Etienne Humblin1, Alice O Kamphorst2.   

Abstract

In this issue of Immunity, Chow et al. (2019) show that the CXCR3-CXCL9 axis is required for reinvigoration of intratumoral CD8+ T cell responses in response to PD-1 blockade and demonstrate that local guidance to dendritic cells, rather than recruitment of T cells into the tumor, underlies the importance of this chemokine axis.
Copyright © 2019 Elsevier Inc. All rights reserved.

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Year:  2019        PMID: 31216458     DOI: 10.1016/j.immuni.2019.05.013

Source DB:  PubMed          Journal:  Immunity        ISSN: 1074-7613            Impact factor:   31.745


  16 in total

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