Literature DB >> 31216455

Death Is Coming and the Clot Thickens, as Pyroptosis Feeds the Fire.

Laura C Burzynski1, Murray C H Clarke2.   

Abstract

Pyroptotic cell death during endotoxemia causes death via unknown mechanisms. In this issue of Immunity, Wu et al. (2019) show that T3SS rod proteins or LPS induces inflammasome activation, macrophage pyroptosis, and accompanying tissue factor release, directly connecting inflammation to coagulation.
Copyright © 2019 Elsevier Inc. All rights reserved.

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Year:  2019        PMID: 31216455     DOI: 10.1016/j.immuni.2019.05.015

Source DB:  PubMed          Journal:  Immunity        ISSN: 1074-7613            Impact factor:   31.745


  5 in total

1.  Gasdermin D-mediated hepatocyte pyroptosis expands inflammatory responses that aggravate acute liver failure by upregulating monocyte chemotactic protein 1/CC chemokine receptor-2 to recruit macrophages.

Authors:  Hong Li; Xue-Ke Zhao; Yi-Ju Cheng; Quan Zhang; Jun Wu; Shuang Lu; Wei Zhang; Yang Liu; Ming-Yu Zhou; Ya Wang; Jing Yang; Ming-Liang Cheng
Journal:  World J Gastroenterol       Date:  2019-11-28       Impact factor: 5.742

2.  Relationship between the pyroptosis of fibroblast‑like synoviocytes and HMGB1 secretion in knee osteoarthritis.

Authors:  Yancheng Xiao; Liang Ding; Songjiang Yin; Zhengquan Huang; Li Zhang; Wei Mei; Peng Wu; Peimin Wang; Ke Pan
Journal:  Mol Med Rep       Date:  2020-12-10       Impact factor: 2.952

3.  Inhibition of lncRNA NEAT1 protects endothelial cells against hypoxia/reoxygenation‑induced NLRP3 inflammasome activation by targeting the miR‑204/BRCC3 axis.

Authors:  Tao Yao; Yiting Song; Shutao Li; Jing Gu; Xuetao Yan
Journal:  Mol Med Rep       Date:  2021-12-01       Impact factor: 2.952

4.  Rapamycin Inhibited Pyroptosis and Reduced the Release of IL-1β and IL-18 in the Septic Response.

Authors:  Luo Zhuo; Xiaobing Chen; Yan Sun; Yanli Wang; Yuanfeng Shi; Lin Bu; Wei Xia; Jiayan Han; Dongmei Chen; Xiaomin Li
Journal:  Biomed Res Int       Date:  2020-08-08       Impact factor: 3.411

Review 5.  Inflammasome activation at the crux of severe COVID-19.

Authors:  Setu M Vora; Judy Lieberman; Hao Wu
Journal:  Nat Rev Immunol       Date:  2021-08-09       Impact factor: 53.106

  5 in total

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