William V Giannobile1, Tord Berglundh2, Bilal Al-Nawas3, Mauricio Araujo4, P Mark Bartold5, Philippe Bouchard6, Iain Chapple7, Reinhard Gruber8, Pernilla Lundberg9, Anton Sculean10, Niklaus P Lang11, Petter Lyngstadaas12, Moritz Kebschull7, Pablo Galindo-Moreno13, Zvi Schwartz14, Lior Shapira15, Andreas Stavropoulos16, Janne Reseland12. 1. Department of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, Michigan, USA. 2. Department of Periodontology, Institute of Odontology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. 3. Department of Oral, Maxillofacial and Plastic Surgery, J. Gutenberg University of Mainz, Mainz, Germany. 4. State University of Maringa, Parana, Brazil. 5. School of Dentistry, University of Adelaide, Adelaide, South Australia, Australia. 6. Department of Periodontology, Paris 7 University, Paris, France. 7. School of Dentistry, Institute of Clinical Sciences, College of Medical & Dental Sciences, University of Birmingham, Birmingham, UK. 8. Department of Oral Biology, Medical University of Vienna, Vienna, Austria. 9. Department of Odontology, Division of Molecular Periodontology, Umeå University, Umeå, Sweden. 10. Department of Periodontology, School of Dental Medicine, University of Bern, Bern, Switzerland. 11. University of Zürich, Zürich, Switzerland. 12. Faculty of Dentistry, University of Oslo, Oslo, Norway. 13. University of Granada, Granada, Spain. 14. Tel Aviv University, Tel Aviv, Israel. 15. Department of Periodontology, Hebrew University of Jerusalem, Jerusalem, Israel. 16. Department of Periodontology, Malmö University, Malmö, Sweden.
Abstract
BACKGROUND AND AIMS: To describe the biology of alveolar bone regeneration. MATERIAL AND METHODS: Four comprehensive reviews were performed on (a) mesenchymal cells and differentiation factors leading to bone formation; (b) the critical interplay between bone resorbing and formative cells; (c) the role of osteoimmunology in the formation and maintenance of alveolar bone; and (d) the self-regenerative capacity following bone injury or tooth extraction were prepared prior to the workshop. RESULTS AND CONCLUSIONS: This summary information adds to the fuller understanding of the alveolar bone regenerative response with implications to reconstructive procedures for patient oral rehabilitation. The group collectively formulated and addressed critical questions based on each of the reviews in this consensus report to advance the field. The report concludes with identified areas of future research.
BACKGROUND AND AIMS: To describe the biology of alveolar bone regeneration. MATERIAL AND METHODS: Four comprehensive reviews were performed on (a) mesenchymal cells and differentiation factors leading to bone formation; (b) the critical interplay between bone resorbing and formative cells; (c) the role of osteoimmunology in the formation and maintenance of alveolar bone; and (d) the self-regenerative capacity following bone injury or tooth extraction were prepared prior to the workshop. RESULTS AND CONCLUSIONS: This summary information adds to the fuller understanding of the alveolar bone regenerative response with implications to reconstructive procedures for patient oral rehabilitation. The group collectively formulated and addressed critical questions based on each of the reviews in this consensus report to advance the field. The report concludes with identified areas of future research.
Authors: Jiordanne Araújo Diniz; Davi da Silva Barbirato; Eduarda Helena Leandro do Nascimento; Andrea Dos Anjos Pontual; Ana Cláudia Amorim Gomes Dourado; José Rodrigues Laureano Filho Journal: Clin Oral Investig Date: 2022-01-22 Impact factor: 3.573