Literature DB >> 31214680

New keys for old locks: carborane-containing drugs as platforms for mechanism-based therapies.

Philipp Stockmann1, Marta Gozzi, Robert Kuhnert, Menyhárt B Sárosi, Evamarie Hey-Hawkins.   

Abstract

Icosahedral carboranes in medicine are still an emerging class of compounds with potential beneficial applications in drug design. These highly hydrophobic clusters are potential "new keys for old locks" which open up an exciting field of research for well-known, but challenging important therapeutic substrates, as demonstrated by the numerous examples discussed in this review.

Entities:  

Mesh：

Substances：

Year:  2019        PMID： 31214680     DOI： 10.1039/c9cs00197b

Source DB:  PubMed          Journal:  Chem Soc Rev        ISSN： 0306-0012            Impact factor:   54.564


  17 in total

1.  The Importance of Strain (Preorganization) in Beryllium Bonds.

Authors:  Ibon Alkorta; José Elguero; Josep M Oliva-Enrich; Manuel Yáñez; Otilia Mó; M Merced Montero-Campillo
Journal:  Molecules       Date:  2020-12-11       Impact factor: 4.411

Review 2.  Boron-Containing Compounds for Prevention, Diagnosis, and Treatment of Human Metabolic Disorders.

Authors:  Córdova-Chávez Ri; Carrasco-Ruiz Mf; Rodríguez-Vera D; Pérez-Capistran T; Tamay-Cach F; Scorei Ir; Abad-García A; Soriano-Ursúa Ma
Journal:  Biol Trace Elem Res       Date:  2022-06-30       Impact factor: 3.738

Review 3.  Preparing (Metalla)carboranes for Nanomedicine.

Authors:  Marta Gozzi; Benedikt Schwarze; Evamarie Hey-Hawkins
Journal:  ChemMedChem       Date:  2021-03-19       Impact factor: 3.466

4.  Ruthenacarborane-Phenanthroline Derivatives as Potential Metallodrugs.

Authors:  Martin Kellert; Imola Sárosi; Rajathees Rajaratnam; Eric Meggers; Peter Lönnecke; Evamarie Hey-Hawkins
Journal:  Molecules       Date:  2020-05-15       Impact factor: 4.411

5.  Fused 1,2-Diboraoxazoles Based on closo-Decaborate Anion-Novel Members of Diboroheterocycle Class.

Authors:  Vera V Voinova; Nikita A Selivanov; Ivan V Plyushchenko; Mikhail F Vokuev; Alexander Yu Bykov; Ilya N Klyukin; Alexander S Novikov; Andrey P Zhdanov; Mikhail S Grigoriev; Igor A Rodin; Konstantin Yu Zhizhin; Nikolay T Kuznetsov
Journal:  Molecules       Date:  2021-01-05       Impact factor: 4.411

6.  Modulation of γ-Secretase Activity by a Carborane-Based Flurbiprofen Analogue.

Authors:  Stefan Saretz; Gabriele Basset; Liridona Useini; Markus Laube; Jens Pietzsch; Dijana Drača; Danijela Maksimović-Ivanić; Johannes Trambauer; Harald Steiner; Evamarie Hey-Hawkins
Journal:  Molecules       Date:  2021-05-11       Impact factor: 4.411

7.  Ruthenacarborane and Quinoline: A Promising Combination for the Treatment of Brain Tumors.

Authors:  Dijana Drača; Milan Marković; Marta Gozzi; Sanja Mijatović; Danijela Maksimović-Ivanić; Evamarie Hey-Hawkins
Journal:  Molecules       Date:  2021-06-22       Impact factor: 4.411

8.  Borcalein: a Carborane-Based Analogue of Baicalein with 12-Lipoxygenase-Independent Toxicity.

Authors:  Robert Kuhnert; Lydia Kuhnert; Menyhárt-B Sárosi; Sven George; Dijana Draca; Svetlana Paskas; Bettina Hofmann; Dieter Steinhilber; Walther Honscha; Sanja Mijatović; Danijela Maksimović-Ivanić; Evamarie Hey-Hawkins
Journal:  ChemMedChem       Date:  2021-11-11       Impact factor: 3.540

9.  Neutral Rhenadicarbaboranes with Re(CO)2(NO) Vertices: A Theoretical Study of Building Blocks for Rhenacarborane-Based Drug Delivery Agents.

Authors:  Amr A A Attia; Alexandru Lupan; Radu Silaghi-Dumitrescu; R Bruce King
Journal:  Molecules       Date:  2019-12-27       Impact factor: 4.411

10.  Quinoline-Conjugated Ruthenacarboranes: Toward Hybrid Drugs with a Dual Mode of Action.

Authors:  Marta Gozzi; Blagoje Murganic; Dijana Drača; John Popp; Peter Coburger; Danijela Maksimović-Ivanić; Sanja Mijatović; Evamarie Hey-Hawkins
Journal:  ChemMedChem       Date:  2019-11-19       Impact factor: 3.466
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.