| Literature DB >> 31212546 |
Lucas D Fernandes1, Luca Ciandrini2.
Abstract
Many theoretical works have attempted to coarse grain gene expression at the level of transcription and translation via frameworks based on exclusion processes. Usually in these models the three-dimensional conformation of the substrates (DNA and mRNA) is neglected, and particles move on a static unidimensional lattice in contact to an infinite reservoir. In this work we generalize the paradigmatic exclusion process and study the transport of particles along a unidimensional polymerlike flexible lattice immersed in a three-dimensional particle reservoir. We study the recycling of particles in the reservoir, how the transport is influenced by the global conformation of the lattice, and, in turn, how particle density dictates the structure of the polymer.Entities:
Year: 2019 PMID: 31212546 DOI: 10.1103/PhysRevE.99.052409
Source DB: PubMed Journal: Phys Rev E ISSN: 2470-0045 Impact factor: 2.529