Literature DB >> 31212546

Driven transport on a flexible polymer with particle recycling: A model inspired by transcription and translation.

Lucas D Fernandes1, Luca Ciandrini2.   

Abstract

Many theoretical works have attempted to coarse grain gene expression at the level of transcription and translation via frameworks based on exclusion processes. Usually in these models the three-dimensional conformation of the substrates (DNA and mRNA) is neglected, and particles move on a static unidimensional lattice in contact to an infinite reservoir. In this work we generalize the paradigmatic exclusion process and study the transport of particles along a unidimensional polymerlike flexible lattice immersed in a three-dimensional particle reservoir. We study the recycling of particles in the reservoir, how the transport is influenced by the global conformation of the lattice, and, in turn, how particle density dictates the structure of the polymer.

Entities:  

Year:  2019        PMID: 31212546     DOI: 10.1103/PhysRevE.99.052409

Source DB:  PubMed          Journal:  Phys Rev E        ISSN: 2470-0045            Impact factor:   2.529


  3 in total

1.  Vectorial channeling as a mechanism for translational control by functional prions and condensates.

Authors:  Xinyu Gu; Nicholas P Schafer; Peter G Wolynes
Journal:  Proc Natl Acad Sci U S A       Date:  2021-11-23       Impact factor: 11.205

2.  What determines eukaryotic translation elongation: recent molecular and quantitative analyses of protein synthesis.

Authors:  Nagammal Neelagandan; Irene Lamberti; Hugo J F Carvalho; Cédric Gobet; Felix Naef
Journal:  Open Biol       Date:  2020-12-09       Impact factor: 6.411

3.  Modelling the effect of ribosome mobility on the rate of protein synthesis.

Authors:  Olivier Dauloudet; Izaak Neri; Jean-Charles Walter; Jérôme Dorignac; Frédéric Geniet; Andrea Parmeggiani
Journal:  Eur Phys J E Soft Matter       Date:  2021-03-08       Impact factor: 1.890

  3 in total

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